SCHEMBL9859720

SCHEMBL9859720

Cc1ccccc1Oc1ccccc1-c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCOA1 Q15788 1/20 0.52
NCOA3 Q9Y6Q9 1/20 0.52
RAB9A P51151 3/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
NPC1 O15118 2/20 0.48
MEN1 O00255 1/20 0.48
TSHR P16473 1/20 0.48
KMT2A Q03164 1/20 0.48
ALDH1A1 P00352 3/20 0.45
KDM4E B2RXH2 2/20 0.45
MAPT P10636 2/20 0.45
PTGS2 P35354 1/20 0.45
HTR7 P34969 1/20 0.44
BRD4 O60885 1/20 0.44
LMNA P02545 2/20 0.44
SCN9A Q15858 2/20 0.43
MAPK1 P28482 2/20 0.43
TP53 P04637 1/20 0.43
ADRB2 P07550 3/20 0.42
L3MBTL1 Q9Y468 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL7781908 0.87 SMN1; SMN2 (0.56) RAB9ASMN1; SMN2NPC1MEN1TSHR
SCHEMBL112422 0.87 NCOA1 (0.63) NCOA1NCOA3RAB9AALDH1A1PTGS2
SCHEMBL10756496 0.84 NCOA1 (0.61) NCOA1NCOA3RAB9AALDH1A1PTGS2
Hydrogen Sulfide SCHEMBL27922694 0.84 NCOA1 (0.61) NCOA1NCOA3RAB9AALDH1A1PTGS2
SCHEMBL6321993 0.84 NCOA1 (0.61) NCOA1NCOA3RAB9AALDH1A1PTGS2
SCHEMBL28436320 0.84 NCOA1 (0.61) NCOA1NCOA3RAB9AALDH1A1PTGS2
SCHEMBL28431579 0.84 NCOA1 (0.61) NCOA1NCOA3RAB9AALDH1A1PTGS2
SCHEMBL2059488 0.82 NCOA1 (0.59) NCOA1NCOA3RAB9AALDH1A1PTGS2
SCHEMBL29637724 0.82 TSHR (0.65) RAB9ASMN1; SMN2NPC1MEN1TSHR
SCHEMBL127000 0.82 TSHR (0.65) RAB9ASMN1; SMN2NPC1MEN1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100532115-C Color developer and thermal recording material containing the same KONISHI CHEM IND (JP) 2009-08-26 CN disclosed
CN-1684840-A Color developer and thermal recording material containing the same KONISHI CHEM IND (JP) 2005-10-19 CN disclosed
CN-1132742-C Thermosensitive recording material NIPPON STEEL CHEMICAL CO.,LTD. (JP) 2003-12-31 CN disclosed
CN-1351544-A Thermosensitive recording material NIPPON STEEL CHEMICAL CO (JP) 2002-05-29 CN disclosed
CN-1318776-A Development composition and thermosensitive recording material MITSUI CHEMICALS INC (JP) 2001-10-24 CN disclosed
EP-0446720-A2 Novel brominated phenoxy compounds and processes for their preparation Bromine Compounds Ltd. (IL) 1991-09-18 EP disclosed
EP-0051235-B1 PROCESS FOR THE PRODUCTION OF DIPHENYL ETHERS HOECHST AKTIENGESELLSCHAFT (DE) 1985-01-09 EP disclosed
EP-0051235-A1 Process for the production of diphenyl ethers HOECHST AKTIENGESELLSCHAFT (DE) 1982-05-12 EP disclosed
US-4229564-A SUITABLE FOR MELT PROCESSING AND EXTRUSION COATINGS RAYCHEM CORPORATION (US) 1980-10-21 US disclosed
US-4111908-A POLYKETONES AND METHODS THEREFOR RAYCHEM CORPORATION (US) 1978-09-05 US disclosed
US-3965146-A POLYMER INTERMEDIATE RAYCHEM CORPORATION (US) 1976-06-22 US disclosed