Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ICMT | O60725 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9100498 | 0.86 | CHRM2 (0.50) | CHRM2CHRM4CHRM1CHRM3SIGMAR1 | |
| SCHEMBL1152495 | 0.81 | CHRM2 (0.43) | CHRM2CHRM4CHRM1CHRM3SIGMAR1 | |
| SCHEMBL9098140 | 0.80 | CHRM2 (0.48) | OPRM1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL1151545 | 0.78 | CYP2D6 (0.47) | OPRM1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL1151922 | 0.78 | CHRM2 (0.43) | CHRM2CHRM4CHRM1CHRM3SIGMAR1 | |
| SCHEMBL1151862 | 0.72 | CHRM2 (0.38) | OPRM1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL27575556 | 0.72 | KDM1A (0.43) | CHRM2CHRM4CHRM1CHRM3SIGMAR1 | |
| SCHEMBL27517581 | 0.70 | KDM1A (0.40) | CHRM2CHRM4CHRM1CHRM3SIGMAR1 | |
| SCHEMBL6473377 | 0.69 | OPRM1 (0.47) | OPRM1OPRL1MAPK1MAPTALDH1A1 | |
| SCHEMBL11761702 | 0.68 | OPRL1 (0.50) | OPRM1OPRL1MAPTNPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10138190-B2 | Process for preparation of ospemifene | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2018-11-27 | — | — | US | disclosed |
| US-20180022674-A1 | PROCESS FOR PREPARATION OF OSPEMIFENE | GLENMARK LIFE SCIENCES LIMITED (IN) | 2018-01-25 | — | — | US | disclosed |
| US-20180022674-A1 | PROCESS FOR PREPARATION OF OSPEMIFENE | GLENMARK LIFE SCIENCES LIMITED (IN) | 2018-01-25 | — | — | US | disclosed |
| US-20180022674-A1 | PROCESS FOR PREPARATION OF OSPEMIFENE | GLENMARK LIFE SCIENCES LIMITED (IN) | 2018-01-25 | — | — | US | disclosed |
| WO-2016110805-A1 | PROCESS FOR PREPARATION OF OSPEMIFENE | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2016-07-14 | — | — | WO | disclosed |
| WO-2016110805-A1 | PROCESS FOR PREPARATION OF OSPEMIFENE | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2016-07-14 | — | — | WO | disclosed |
| US-4996225-A | Antitumor agents | FARMOS GROUP LTD. (FI) | 1991-02-26 | — | — | US | disclosed |
| US-4696949-A | ANTITUMOR AGENTS, ANTIESTROGENS | FARMOS GROUP LTD. (FI) | 1987-09-29 | — | — | US | disclosed |
| EP-0095875-B1 | NOVEL TRI-PHENYL ALKANE AND ALKENE DERIVATIVES AND THEIR PREPARATION AND USE | Farmos Group Ltd. (FI) | 1986-09-10 | — | — | EP | disclosed |
| EP-0095875-A2 | Novel tri-phenyl alkane and alkene derivatives and their preparation and use | Farmos Group Ltd. (FI) | 1983-12-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10138190-B2 | Process for preparation of ospemifene | CYP3A4, MME, CYP4B1 | OPRM1 4/4885OPRL1 71/4885CHRM2 803/4885 |
| US-20180022674-A1 | PROCESS FOR PREPARATION OF OSPEMIFENE | CYP3A4, MME, CYP4B1 | OPRM1 4/4885OPRL1 71/4885CHRM2 803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.