Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9859941 | 1.00 | HMGCR (0.38) | HMGCRLMNAMEN1MAPTRECQL | |
| SCHEMBL9860005 | 0.86 | HMGCR (0.48) | HMGCR | |
| SCHEMBL9860008 | 0.86 | HMGCR (0.48) | HMGCR | |
| SCHEMBL9860221 | 0.74 | HMGCR (0.41) | HMGCRMAPTALDH1A1KDM4ECYP1A2 | |
| SCHEMBL9860226 | 0.74 | HMGCR (0.41) | HMGCRMAPTALDH1A1KDM4ECYP1A2 | |
| SCHEMBL9860172 | 0.73 | MAPT (0.37) | LMNAMEN1MAPTRECQLKMT2A | |
| SCHEMBL9860180 | 0.73 | MAPT (0.37) | LMNAMEN1MAPTRECQLKMT2A | |
| SCHEMBL9769870 | 0.73 | HMGCR (0.68) | HMGCRALDH1A1 | |
| SCHEMBL9769865 | 0.73 | HMGCR (0.68) | HMGCRALDH1A1 | |
| SCHEMBL9859442 | 0.73 | MAPT (0.40) | LMNAMEN1MAPTRECQLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430129-A2 | Novel phenylethylene derivatives, processes for preparing the same and intermediates therefor | TANABE SEIYAKU CO., LTD. (JP) | 1991-06-05 | — | — | EP | disclosed |