Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9860172 | 1.00 | MAPT (0.37) | MAPTMEN1KMT2ARECQLKDM4E | |
| SCHEMBL9859442 | 0.86 | MAPT (0.40) | MAPTMEN1KMT2ARECQLKDM4E | |
| SCHEMBL9859941 | 0.73 | HMGCR (0.38) | MAPTMEN1KMT2ARECQLKDM4E | |
| SCHEMBL9860005 | 0.73 | HMGCR (0.48) | — | |
| SCHEMBL9860008 | 0.73 | HMGCR (0.48) | — | |
| SCHEMBL9859934 | 0.73 | HMGCR (0.38) | MAPTMEN1KMT2ARECQLKDM4E | |
| SCHEMBL9859889 | 0.72 | LMNA (0.41) | MAPTMEN1KMT2ARECQLKDM4E | |
| SCHEMBL14539264 | 0.71 | MAPT (0.44) | MAPTMEN1KMT2ARECQLKDM4E | |
| SCHEMBL9769899 | 0.67 | HMGCR (0.54) | LMNAALDH1A1RAB9ANPC1TSHR | |
| SCHEMBL9769871 | 0.67 | HMGCR (0.54) | LMNAALDH1A1RAB9ANPC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430129-A2 | Novel phenylethylene derivatives, processes for preparing the same and intermediates therefor | TANABE SEIYAKU CO., LTD. (JP) | 1991-06-05 | — | — | EP | disclosed |