Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 14/20 | 0.58 |
| ▸ | GSTA1 | P08263 | 8/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.58 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | MAP2K6 | P52564 | 1/20 | 0.58 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.58 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.58 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6210580 | 0.83 | GSTP1 (0.58) | GSTP1GSTA1MEN1ABCC3PLIN1 | |
| SCHEMBL13284005 | 0.79 | GSTP1 (0.70) | GSTP1GSTA1MEN1ABCC3PLIN1 | |
| SCHEMBL10846560 | 0.78 | HSP90AB1 (0.53) | GSTP1GSTA1MEN1ABCC3PLIN1 | |
| SCHEMBL20088748 | 0.78 | GSTP1 (0.77) | GSTP1GSTA1MEN1ABCC3PLIN1 | |
| SCHEMBL8506844 | 0.76 | GSTP1 (0.67) | GSTP1GSTA1MEN1ABCC3PLIN1 | |
| Ethacrynic Acid SCHEMBL26353 | 0.74 | GSTP1 (1.00) | GSTP1GSTA1MEN1ABCC3PLIN1 | |
| SCHEMBL10014667 | 0.74 | GSTP1 (0.80) | GSTP1GSTA1MEN1ABCC3PLIN1 | |
| SCHEMBL21159860 | 0.74 | GSTP1 (0.50) | GSTP1GSTA1MEN1ABCC3PLIN1 | |
| SCHEMBL8986308 | 0.74 | GSTP1 (0.71) | GSTP1GSTA1MEN1ABCC3PLIN1 | |
| Ethacrynic Acid SCHEMBL9108011 | 0.74 | GSTP1 (1.00) | GSTP1GSTA1MEN1ABCC3PLIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1234792-A | Nitrate ester derivatives and their use in the treatment of urinary incontinence and other disorders | NICOX SA (FR) | 1999-11-10 | — | — | CN | claimed |
| CN-104334131-A | Ophthalmic drug delivery device and methods of use | UNIV DUKE | 2015-02-04 | — | — | CN | disclosed |
| CN-1234792-A | Nitrate ester derivatives and their use in the treatment of urinary incontinence and other disorders | NICOX SA (FR) | 1999-11-10 | — | — | CN | disclosed |
| EP-0431248-A1 | Process for preparation of alpha-aryloxy acetic acids and their salts | G.D. Searle & Co. (US) | 1991-06-12 | — | — | EP | disclosed |
| US-4952724-A | Process for preparation of alpha-aryloxy acetic acids and their salts | G. D. SEARLE & CO. (US) | 1990-08-28 | — | — | US | disclosed |
| US-4390537-A | ANTIALLERGENS | MERCK & CO., INC. (US) | 1983-06-28 | — | — | US | disclosed |
| US-4342782-A | PROCESS FOR TEATING ALLERGIES | MERCK & CO., INC. (US) | 1982-08-03 | — | — | US | disclosed |
| US-4070539-A | DIURETICS, SALURETICS | MERCK & CO., INC. (US) | 1978-01-24 | — | — | US | disclosed |