Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7379214 | 0.88 | KMT2A (0.43) | TDP1KMT2ACASP3RAB9APOLB | |
| SCHEMBL8554986 | 0.84 | TDP1 (0.42) | TDP1KMT2ALMNAMAPTRAB9A | |
| SCHEMBL11996368 | 0.82 | NR1H2 (0.42) | TDP1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL10719288 | 0.81 | TDP1 (0.46) | TDP1CASP3LMNAMAPTRAB9A | |
| SCHEMBL8688235 | 0.78 | LMNA (0.45) | TDP1KMT2ALMNASMN1; SMN2POLB | |
| SCHEMBL9831506 | 0.75 | TDP1 (0.41) | TDP1CASP3LMNAPOLBALDH1A1 | |
| SCHEMBL14681655 | 0.74 | TDP1 (0.55) | TDP1KMT2ALMNAMAPTRAB9A | |
| SCHEMBL14681604 | 0.74 | TDP1 (0.55) | TDP1KMT2ALMNAMAPTRAB9A | |
| SCHEMBL6364898 | 0.72 | TDP1 (0.52) | TDP1KMT2ACASP3LMNARAB9A | |
| SCHEMBL5490233 | 0.72 | TDP1 (0.52) | TDP1KMT2ACASP3LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988828-A | Antiulcer agents, antagonist for histamine H2 receptors | FUJIREBIO KABUSHIKI KAISHA (JP) | 1991-01-29 | — | — | US | disclosed |
| EP-0318036-A2 | Phenoxypropyl derivatives | FUJIREBIO KABUSHIKI KAISHA (JP) | 1989-05-31 | — | — | EP | disclosed |