Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15241103 | 0.88 | TDP1 (0.46) | TDP1CASP3LMNAALDH1A1GAA | |
| SCHEMBL15240556 | 0.88 | TDP1 (0.46) | TDP1CASP3LMNAALDH1A1GAA | |
| SCHEMBL7054656 | 0.88 | TDP1 (0.46) | TDP1CASP3LMNAALDH1A1GAA | |
| SCHEMBL14479254 | 0.85 | TDP1 (0.44) | TDP1CASP3LMNAALDH1A1POLB | |
| SCHEMBL19285617 | 0.84 | CASP3 (0.46) | TDP1CASP3LMNAALDH1A1GAA | |
| SCHEMBL11685677 | 0.84 | TNF (0.52) | TDP1LMNAALDH1A1GAAPOLB | |
| SCHEMBL19285667 | 0.84 | CASP3 (0.46) | TDP1CASP3LMNAALDH1A1GAA | |
| SCHEMBL19285619 | 0.84 | CASP3 (0.46) | TDP1CASP3LMNAALDH1A1GAA | |
| SCHEMBL18909733 | 0.83 | TDP1 (0.49) | TDP1CASP3LMNAALDH1A1GAA | |
| SCHEMBL12382279 | 0.83 | TERT (0.41) | TDP1LMNAALDH1A1GALR3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230321124-A1 | ROR gamma t Inhibitors and Topical Uses Thereof | DERMIRA, INC. | 2023-10-12 | — | — | US | disclosed |
| US-20230260787-A1 | COMPOSITION FOR FORMING PROTECTIVE FILM AGAINST ALKALINE AQUEOUS HYDROGEN PEROXIDE, SUBSTRATE FOR PRODUCING SEMICONDUCTOR APPARATUS, METHOD FOR FORMING PROTECTIVE FILM, AND METHOD FOR FORMING PATTERN | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-08-17 | — | — | US | disclosed |
| WO-2021106627-A1 | POLYIMIDE, POLYIMIDE RESIN FILM, MULTILAYER BODY AND FLEXIBLE DEVICE | 東レ株式会社 | 2021-06-03 | — | — | WO | disclosed |
| US-20200172731-A1 | BINDER RESIN FOR ELECTRODES, ELECTRODE MIXTURE PASTE, ELECTRODE AND METHOD FOR PRODUCING ELECTRODE | UBE CORPORATION (JP) | 2020-06-04 | — | — | US | disclosed |
| US-9834520-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-12-05 | — | — | US | disclosed |
| WO-2012068439-A1 | OPTICAL ARTICLE WITH LENS COMPRISING POLYIMIDE | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2012-05-24 | — | — | WO | disclosed |
| US-6858070-B1 | Phase change inks | XEROX CORPORATION (US) | 2005-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230321124-A1 | ROR gamma t Inhibitors and Topical Uses Thereof | RORC, RORB, RORA | TDP1 3589/4885CASP3 4586/4885LMNA 4810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.