Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.34 |
| ▸ | PTPN7 | P35236 | 3/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | SELP | P16109 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10483214 | 0.89 | LMNA (0.34) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL28738554 | 0.89 | LMNA (0.34) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL9626212 | 0.85 | MEN1 (0.41) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL9626661 | 0.85 | PTPN7 (0.38) | MEN1KMT2AALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL27988190 | 0.85 | PTPN7 (0.38) | MEN1KMT2AALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL9626095 | 0.85 | PTPN7 (0.38) | MEN1KMT2AALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL9340006 | 0.85 | PTPN7 (0.38) | MEN1KMT2AALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL28072019 | 0.85 | PTPN7 (0.38) | MEN1KMT2AALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL9626359 | 0.85 | HMGCR (0.53) | MEN1KMT2AALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7642174 | 0.83 | PTPN7 (0.35) | MEN1KMT2AALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988716-A | Inhibitors of slow reacting substance of anaphylaxis | SCHERING CORPORATION (US) | 1991-01-29 | — | — | US | disclosed |
| US-4889873-A | Inhibitors of slow reacting substance of anaphylaxis | SCHERING CORPORATION (US) | 1989-12-26 | — | — | US | disclosed |
| US-4798842-A | Inhibitors of slow reacting substance of anaphylaxis | SCHERING CORPORATION (US) | 1989-01-17 | — | — | US | disclosed |