SCHEMBL9860352

SCHEMBL9860352

C=C(O)CN1CCN(C)CC1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
STAT6 P42226 1/20 0.44
TSHR P16473 1/20 0.39
MC4R P32245 1/20 0.39
KMT2A Q03164 2/20 0.38
GAA P10253 2/20 0.37
SIGMAR1 Q99720 2/20 0.37
PAOX Q6QHF9 1/20 0.36
ALOX15 P16050 1/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
LMNA P02545 1/20 0.35
PHGDH O43175 1/20 0.34
MGLL Q99685 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24709327 0.89 HSD17B10 (0.44) ALDH1A1SMN1; SMN2STAT6TSHRKMT2A
SCHEMBL11875598 0.87
SCHEMBL10694476 0.87 ALDH1A1 (0.55) ALDH1A1SMN1; SMN2STAT6
SCHEMBL17085987 0.87 ALDH1A1 (0.55) ALDH1A1SMN1; SMN2STAT6
SCHEMBL10248689 0.80 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2STAT6TSHRMC4R
SCHEMBL10283317 0.78 ALDH1A1 (0.76) ALDH1A1SMN1; SMN2STAT6TSHRMC4R
SCHEMBL11650704 0.78 KMT2A (0.44) ALDH1A1SMN1; SMN2STAT6TSHRKMT2A
SCHEMBL3214745 0.76
SCHEMBL3626700 0.75 HSD17B10 (0.52) ALDH1A1SMN1; SMN2TSHRKMT2AGAA
SCHEMBL8038150 0.75 HSD17B10 (0.52) ALDH1A1SMN1; SMN2TSHRKMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0210440-B1 CATALYST FOR PRODUCING POLYURETHANE FOAMS COATED WITH A SKIN Tosoh Corporation (JP) 1991-12-11 EP claimed
US-4701473-A 4-METHYL-1-(2-HYDROXYALKYL)-PIPERAZINE TOYO SODA MANUFACTURING CO., LTD. (JP) 1987-10-20 US claimed
EP-0210440-A1 Catalyst for producing polyurethane foams coated with a skin Tosoh Corporation (JP) 1987-02-04 EP claimed
JP-62000514-A None JP disclosed
EP-0210440-B1 CATALYST FOR PRODUCING POLYURETHANE FOAMS COATED WITH A SKIN Tosoh Corporation (JP) 1991-12-11 EP disclosed
US-4701473-A 4-METHYL-1-(2-HYDROXYALKYL)-PIPERAZINE TOYO SODA MANUFACTURING CO., LTD. (JP) 1987-10-20 US disclosed
US-4701473-A 4-METHYL-1-(2-HYDROXYALKYL)-PIPERAZINE TOYO SODA MANUFACTURING CO., LTD. (JP) 1987-10-20 US disclosed
EP-0239391-A2 1,2,6-triphenyl-4(1H)-pyridinone and pyridinethione derivatives, production and uses thereof KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1987-09-30 EP disclosed
EP-0210440-A1 Catalyst for producing polyurethane foams coated with a skin Tosoh Corporation (JP) 1987-02-04 EP disclosed
EP-0210440-A1 Catalyst for producing polyurethane foams coated with a skin Tosoh Corporation (JP) 1987-02-04 EP disclosed
JP-S62514-A CATALYST FOR PRODUCING POLYURETHANE FOAM WITH SKIN TOYO SODA MFG CO LTD 1987-01-06 JP disclosed