Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A2 | Q12908 | 5/20 | 0.71 |
| ▸ | PDE1A | P54750 | 3/20 | 0.41 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.41 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.41 |
| ▸ | ERN1 | O75460 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9860654 | 0.98 | SLC10A2 (0.68) | SLC10A2PDE1APDE1BPDE1CPDE3B | |
| SCHEMBL9860596 | 0.96 | SLC10A2 (0.71) | SLC10A2PDE1APDE1BPDE1CPDE3B | |
| SCHEMBL8688163 | 0.91 | SLC10A2 (0.76) | SLC10A2PDE1APDE1BPDE1CPDE3B | |
| SCHEMBL29740792 | 0.91 | SLC10A2 (0.76) | SLC10A2PDE1APDE1BPDE1CPDE3B | |
| SCHEMBL9861079 | 0.91 | SLC10A2 (0.73) | SLC10A2PDE1APDE1BPDE1CPDE3B | |
| SCHEMBL9860682 | 0.91 | SLC10A2 (0.73) | SLC10A2PDE1APDE1BPDE1CPDE3B | |
| SCHEMBL9777718 | 0.90 | SLC10A2 (0.74) | SLC10A2PDE1APDE1BPDE1CPDE3B | |
| SCHEMBL9777712 | 0.90 | SLC10A2 (0.74) | SLC10A2PDE1APDE1BPDE1CPDE3B | |
| SCHEMBL9860659 | 0.90 | SLC10A2 (0.66) | SLC10A2PDE1APDE1BPDE1CPDE3B | |
| SCHEMBL8683220 | 0.88 | SLC10A2 (0.80) | SLC10A2PDE1APDE1BPDE1CPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5070103-A | ANTILIPEMIC AGENTS, ARTERIOSCLEROSIS | TANABE SEIYAKU CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |
| EP-0188248-B1 | NAPHTHALENE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | TANABE SEIYAKU CO., LTD. (JP) | 1990-07-11 | — | — | EP | disclosed |
| US-4897418-A | ANTILIPEMIC AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1990-01-30 | — | — | US | disclosed |
| US-4771072-A | HYPOLIPIDEMIC ACTIVITY | TANABE SEIYAKU CO., LTD. (JP) | 1988-09-13 | — | — | US | disclosed |
| EP-0188248-A2 | Naphthalene derivatives, process for the preparation thereof and pharmaceutical composition containing same | TANABE SEIYAKU CO., LTD. (JP) | 1986-07-23 | — | — | EP | disclosed |