Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A2 | Q12908 | 5/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.46 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.46 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.46 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.46 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.44 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9861079 | 1.00 | SLC10A2 (0.73) | SLC10A2ALDH1A1GAATUBB4ATUBB | |
| SCHEMBL9789879 | 0.97 | SLC10A2 (0.68) | SLC10A2ALDH1A1GAATUBB4ATUBB | |
| SCHEMBL29740792 | 0.93 | SLC10A2 (0.76) | SLC10A2ALDH1A1PDE1APDE1BPDE3B | |
| SCHEMBL8688163 | 0.93 | SLC10A2 (0.76) | SLC10A2ALDH1A1PDE1APDE1BPDE3B | |
| SCHEMBL9777712 | 0.92 | SLC10A2 (0.74) | SLC10A2ALDH1A1GAAPDE1APDE1B | |
| SCHEMBL9777718 | 0.92 | SLC10A2 (0.74) | SLC10A2ALDH1A1PDE1APDE1BPDE3B | |
| SCHEMBL9860596 | 0.91 | SLC10A2 (0.71) | SLC10A2DPP4PDE1APDE1BPDE3B | |
| SCHEMBL9860425 | 0.91 | SLC10A2 (0.71) | SLC10A2ALDH1A1GAADPP4PDE1A | |
| SCHEMBL9860654 | 0.89 | SLC10A2 (0.68) | SLC10A2ALDH1A1GAADPP4PDE1A | |
| SCHEMBL8683220 | 0.89 | SLC10A2 (0.80) | SLC10A2ALDH1A1PDE1APDE1BPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5070103-A | ANTILIPEMIC AGENTS, ARTERIOSCLEROSIS | TANABE SEIYAKU CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |
| EP-0188248-B1 | NAPHTHALENE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | TANABE SEIYAKU CO., LTD. (JP) | 1990-07-11 | — | — | EP | disclosed |
| US-4897418-A | ANTILIPEMIC AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1990-01-30 | — | — | US | disclosed |
| CN-1006464-B | PROCESS FOR PREPARING NAPHTHALENE DERIVATIVES | TANABE SEIYAKU CO (JP) | 1990-01-17 | — | — | CN | disclosed |
| US-4771072-A | HYPOLIPIDEMIC ACTIVITY | TANABE SEIYAKU CO., LTD. (JP) | 1988-09-13 | — | — | US | disclosed |
| EP-0188248-A2 | Naphthalene derivatives, process for the preparation thereof and pharmaceutical composition containing same | TANABE SEIYAKU CO., LTD. (JP) | 1986-07-23 | — | — | EP | disclosed |