Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 3/20 | 0.57 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.57 |
| ▸ | ITGAL | P20701 | 3/20 | 0.57 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.51 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.51 |
| ▸ | REN | P00797 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | ECE1 | P42892 | 1/20 | 0.45 |
| ▸ | QPCT | Q16769 | 1/20 | 0.45 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20397513 | 0.90 | ITGB2 (0.50) | ITGB2ICAM1ITGALSLC15A2CA1 | |
| SCHEMBL15683044 | 0.89 | ITGB2 (0.64) | ITGB2ICAM1ITGALSLC15A2CA1 | |
| SCHEMBL468830 | 0.89 | ITGB2 (0.64) | ITGB2ICAM1ITGALSLC15A2CA1 | |
| SCHEMBL6026427 | 0.89 | ITGB2 (0.64) | ITGB2ICAM1ITGALSLC15A2CA1 | |
| Water SCHEMBL8680774 | 0.88 | ITGB2 (0.63) | ITGB2ICAM1ITGALSLC15A2CA1 | |
| SCHEMBL30656637 | 0.85 | ITGB2 (0.53) | ITGB2ICAM1ITGALSLC15A2CA1 | |
| SCHEMBL308989 | 0.84 | ITGB2 (0.59) | ITGB2ICAM1ITGALSLC15A2CA1 | |
| SCHEMBL1229751 | 0.84 | ITGB2 (0.59) | ITGB2ICAM1ITGALSLC15A2CA1 | |
| SCHEMBL1161012 | 0.84 | ITGB2 (0.59) | ITGB2ICAM1ITGALSLC15A2CA1 | |
| SCHEMBL11559043 | 0.84 | ITGB2 (0.59) | ITGB2ICAM1ITGALSLC15A2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023139608-A1 | Synergistic Compositions For Enhancing TFEB-Mediated Intracellular Clearance | Celagenex Research (India) Pvt. Ltd. (IN) | 2023-07-27 | — | — | WO | disclosed |
| US-4994457-A | Piroxicam, 5'-guanylic acid, and(or) N-acetyl-L-methionine | PFIZER INC. (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0218453-B1 | IMPROVED ANTIINFLAMMATORY COMPOSITIONS AND METHODS | PFIZER INC. (US) | 1990-01-03 | — | — | EP | disclosed |
| EP-0218453-A1 | Improved antiinflammatory compositions and methods | PFIZER INC. (US) | 1987-04-15 | — | — | EP | disclosed |