Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 3/20 | 0.50 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.50 |
| ▸ | ITGAL | P20701 | 3/20 | 0.50 |
| ▸ | REN | P00797 | 5/20 | 0.49 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.48 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9860623 | 0.90 | ITGB2 (0.57) | ITGB2ICAM1ITGALRENSLC15A2 | |
| SCHEMBL15683044 | 0.85 | ITGB2 (0.64) | ITGB2ICAM1ITGALRENSLC15A2 | |
| SCHEMBL468830 | 0.85 | ITGB2 (0.64) | ITGB2ICAM1ITGALRENSLC15A2 | |
| SCHEMBL6026427 | 0.85 | ITGB2 (0.64) | ITGB2ICAM1ITGALRENSLC15A2 | |
| Water SCHEMBL8680774 | 0.83 | ITGB2 (0.63) | ITGB2ICAM1ITGALRENSLC15A2 | |
| SCHEMBL30656637 | 0.81 | ITGB2 (0.53) | ITGB2ICAM1ITGALRENSLC15A2 | |
| SCHEMBL29391246 | 0.81 | SLC15A2 (0.56) | ITGB2ICAM1ITGALRENSLC15A2 | |
| SCHEMBL11559043 | 0.80 | ITGB2 (0.59) | ITGB2ICAM1ITGALSLC15A2ACE2 | |
| SCHEMBL18862361 | 0.80 | SLC15A2 (0.51) | ITGB2ICAM1ITGALRENSLC15A2 | |
| SCHEMBL27906686 | 0.78 | SLC15A2 (0.58) | ITGB2ICAM1ITGALRENSLC15A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210000972-A1 | NANOPARTICLES FOR SUSTAINED OPHTHALMIC DRUG DELIVERY AND METHODS OF USE | NEWPORT SCIENTIFIC, INC. | 2021-01-07 | — | — | US | disclosed |
| US-20180207293-A1 | NANOPARTICLES FOR SUSTAINED OPHTHALMIC DRUG DELIVERY AND METHODS OF USE | NEWPORT SCIENTIFIC, INC. | 2018-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180207293-A1 | NANOPARTICLES FOR SUSTAINED OPHTHALMIC DRUG DELIVERY AND METHODS OF USE | UACA, CRYAA, CRYAB | ITGB2 702/4885ICAM1 202/4885ITGAL 628/4885 |
| US-20210000972-A1 | NANOPARTICLES FOR SUSTAINED OPHTHALMIC DRUG DELIVERY AND METHODS OF USE | CHRNA1, CHRNB1, NPY1R | ITGB2 1148/4885ICAM1 419/4885ITGAL 763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.