Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ABAT | P80404 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | PTPRC | P08575 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodohippurate SCHEMBL589803 | 0.98 | KMT2A (0.58) | KMT2AMEN1TDP1KEAP1EGLN1 | |
| Iodohippurate SCHEMBL29959499 | 0.98 | KMT2A (0.58) | KMT2AMEN1TDP1KEAP1EGLN1 | |
| Iodohippurate SCHEMBL2142713 | 0.96 | KMT2A (0.56) | KMT2AMEN1TDP1KEAP1EGLN1 | |
| Iodohippurate SCHEMBL5915006 | 0.96 | KMT2A (0.56) | KMT2AMEN1TDP1KEAP1EGLN1 | |
| SCHEMBL31448014 | 0.85 | KEAP1 (0.62) | KMT2AKEAP1EGLN1KDM4CKDM4E | |
| SCHEMBL5532912 | 0.84 | KEAP1 (0.51) | KMT2AMEN1TDP1KEAP1EGLN1 | |
| SCHEMBL11325406 | 0.82 | KMT2A (0.51) | KMT2AMEN1TDP1KEAP1SIGMAR1 | |
| SCHEMBL8814831 | 0.82 | KMT2A (0.51) | KMT2AMEN1TDP1KEAP1SIGMAR1 | |
| Iodohippurate SCHEMBL5915003 | 0.81 | KMT2A (0.50) | KMT2AMEN1TDP1KEAP1SIGMAR1 | |
| Iodohippurate SCHEMBL1652159 | 0.81 | KMT2A (0.50) | KMT2AMEN1TDP1KEAP1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1689120-B | Multiple hazard prevention article and method of making same | MERIDIAN RES & DEV | 2012-05-09 | — | — | CN | claimed |
| CN-1689120-A | Multiple hazard prevention article and method of making same | MERIDIAN RES & DEV (US) | 2005-10-26 | — | — | CN | claimed |
| CN-1689120-B | Multiple hazard prevention article and method of making same | MERIDIAN RES & DEV | 2012-05-09 | — | — | CN | disclosed |
| CN-101010107-A | Luminescent metal complexes for monitoring renal function | MALLINCKRODT INC (US) | 2007-08-01 | — | — | CN | disclosed |
| CN-1689120-A | Multiple hazard prevention article and method of making same | MERIDIAN RES & DEV (US) | 2005-10-26 | — | — | CN | disclosed |
| US-5021220-A | Haluaromatic compound, water-soluble acid, copper salt acid-stable reducing agent | MALLINCKRODT, INC. (US) | 1991-06-04 | — | — | US | disclosed |
| US-4942231-A | CATALYTIC HALOGENATION IN THE PRESENCE OF A REDUCING AGENT AND ACID MEDIUM | MALLINCKRODT, INC. (US) | 1990-07-17 | — | — | US | disclosed |
| EP-0165630-B1 | METHOD OF PREPARING A CHLORINATED, BROMINATED, RADIOBROMINATED, IODINATED AND/OR RADIOIODINATED, AROMATIC OR HETEROAROMATIC COMPOUND, AS WELL AS A KIT FOR PREPARING A DIAGNOSTIC COMPOSITION ON THE BASIS OF THIS COMPOUND | MALLINCKRODT, INC.(a Missouri corporation) (US) | 1989-10-18 | — | — | EP | disclosed |
| US-4584186-A | RADIODIAGNOSIS OF RENAL FUNCTION | Mallinckrodt, Diagnostica (Holland) B.V. (NL) | 1986-04-22 | — | — | US | disclosed |
| EP-0165630-A2 | Method of preparing a chlorinated, brominated, radiobrominated, iodinated and/or radioiodinated, aromatic or heteroaromatic compound, as well as a kit for preparing a diagnostic composition on the basis of this compound | MALLINCKRODT, INC.(a Missouri corporation) (US) | 1985-12-27 | — | — | EP | disclosed |
| EP-0113135-A2 | Radiolabelled metallocene derivatives | Mallinckrodt Diagnostica (Holland) B.V. (NL) | 1984-07-11 | — | — | EP | disclosed |
| US-4307072-A | X-RAY CONTRAST AGENTS | MALLINCKRODT, INC. (US) | 1981-12-22 | — | — | US | disclosed |