Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11228311 | 0.98 | LMNA (0.58) | LMNAF2TSHRTDP1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL8998037 | 0.95 | LMNA (0.56) | LMNAF2TSHRTDP1ALDH1A1 | |
| SCHEMBL28396362 | 0.95 | LMNA (0.56) | LMNAF2TSHRTDP1ALDH1A1 | |
| SCHEMBL38663324 | 0.84 | LMNA (0.58) | LMNAF2TSHRTDP1ALDH1A1 | |
| SCHEMBL15971711 | 0.82 | TSHR (0.55) | TSHRALDH1A1TP53MAPTCES2 | |
| SCHEMBL20916961 | 0.80 | LMNA (0.54) | LMNAF2TSHRTDP1ALDH1A1 | |
| SCHEMBL11529434 | 0.77 | LMNA (0.56) | LMNAF2TSHRTDP1ALDH1A1 | |
| SCHEMBL28937233 | 0.77 | TSHR (0.57) | LMNAF2TSHRTDP1ALDH1A1 | |
| SCHEMBL28326886 | 0.77 | LMNA (0.50) | LMNAF2TSHRTDP1ALDH1A1 | |
| SCHEMBL16897300 | 0.76 | CES2 (0.50) | KMT2AMAPTMAPK1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041622-A | Heating polyisobutylene, maleic anhydride and chlorine; acylating agents; additives in lubricants and fuels | THE LUBRIZOL CORPORATION (US) | 1991-08-20 | — | — | US | disclosed |