Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.37 |
| ▸ | NOS1 | P29475 | 2/20 | 0.37 |
| ▸ | NOS2 | P35228 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4039461 | 1.00 | NOS3 (0.37) | NOS3NOS1NOS2ALDH1A1KDM4E | |
| SCHEMBL4039458 | 1.00 | NOS3 (0.37) | NOS3NOS1NOS2ALDH1A1KDM4E | |
| SCHEMBL9740100 | 0.94 | — | — | |
| SCHEMBL9740105 | 0.94 | — | — | |
| SCHEMBL31621900 | 0.84 | NOS1 (0.37) | NOS3NOS1NOS2ALDH1A1KDM4E | |
| SCHEMBL11154190 | 0.81 | NOS1 (0.40) | NOS3NOS1NOS2ALDH1A1KDM4E | |
| SCHEMBL11154919 | 0.81 | NOS1 (0.40) | NOS3NOS1NOS2ALDH1A1KDM4E | |
| SCHEMBL27452592 | 0.80 | NOS1 (0.41) | NOS1NOS2ALDH1A1KDM4ENPC1 | |
| SCHEMBL28122037 | 0.80 | SMN1; SMN2 (0.43) | NOS3NOS1NOS2ALDH1A1KDM4E | |
| SCHEMBL6922607 | 0.79 | KMT2A (0.35) | ALDH1A1KDM4EHPGDSMN1; SMN2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0074472-B2 | CONTINUOUS HYDROLYSIS OF KETOXIME | ALLIED CORPORATION (US) | 1991-08-21 | — | — | EP | disclosed |
| EP-0074472-B1 | CONTINUOUS HYDROLYSIS OF KETOXIME | ALLIED CORPORATION (US) | 1987-06-24 | — | — | EP | disclosed |
| US-4349520-A | BY STEAM DISTILLATION PRODUCING A KETONE AND HYDROXYAMMONIUM SALT | ALLIED CORPORATION (US) | 1982-09-14 | — | — | US | disclosed |