Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9860970 | 0.95 | ALDH1A1 (0.40) | KDM4EALDH1A1RAB9AATML3MBTL1 | |
| SCHEMBL9861394 | 0.89 | MAPT (0.40) | KDM4EALDH1A1SMN1; SMN2LMNARECQL | |
| SCHEMBL9861514 | 0.84 | KCNA3 (0.52) | ALDH1A1L3MBTL1RECQLPKM | |
| SCHEMBL9861157 | 0.83 | KCNA3 (0.50) | ALDH1A1RAB9ASMN1; SMN2LMNAPOLB | |
| SCHEMBL9861795 | 0.83 | KCNA3 (0.50) | ALDH1A1RAB9ASMN1; SMN2LMNAPOLB | |
| SCHEMBL9861091 | 0.80 | KCNA3 (0.48) | ALDH1A1L3MBTL1RECQLNPC1PKM | |
| SCHEMBL9861831 | 0.75 | RAB9A (0.46) | ALDH1A1RAB9ASMN1; SMN2LMNANPC1 | |
| SCHEMBL9861080 | 0.74 | HRH3 (0.47) | KDM4ESMN1; SMN2LMNAHTTDRD4 | |
| SCHEMBL9860989 | 0.74 | KDM4E (0.46) | KDM4EALDH1A1RAB9AATML3MBTL1 | |
| SCHEMBL17445905 | 0.74 | ATM (0.60) | KDM4EALDH1A1RAB9AATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150168-B1 | USE OF METAL SALTS OF THIOSULPHURIC -S-ESTERS AS RUBBER/METAL BONDING PROMOTERS | MONSANTO EUROPE S.A./N.V. (BE) | 1991-05-08 | — | — | EP | disclosed |
| US-4581297-A | STEEL BELTED RADIAL TIRES | MONSANTO EUROPE, S.A. (BE) | 1986-04-08 | — | — | US | disclosed |