Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.72 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.72 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.72 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.72 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.72 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.72 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.72 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.72 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.72 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.72 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.72 |
| ▸ | NAAA | Q02083 | 1/20 | 0.72 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | NAMPT | P43490 | 2/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6170086 | 0.94 | NPC1 (0.66) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL9452844 | 0.92 | HDAC1 (0.82) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL20734829 | 0.92 | HDAC1 (0.82) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL9489756 | 0.92 | HDAC1 (0.82) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL9489804 | 0.92 | HDAC1 (0.82) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL9492235 | 0.92 | HDAC1 (0.82) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL7460068 | 0.92 | HDAC1 (0.82) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL9188890 | 0.92 | HDAC1 (0.82) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL9492328 | 0.92 | HDAC1 (0.82) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL2923674 | 0.90 | MAPK1 (0.67) | HDAC1HDAC2HDAC8HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150168-B1 | USE OF METAL SALTS OF THIOSULPHURIC -S-ESTERS AS RUBBER/METAL BONDING PROMOTERS | MONSANTO EUROPE S.A./N.V. (BE) | 1991-05-08 | — | — | EP | disclosed |
| US-4581297-A | STEEL BELTED RADIAL TIRES | MONSANTO EUROPE, S.A. (BE) | 1986-04-08 | — | — | US | disclosed |
| EP-0150168-A2 | Use of metal salts of thiosulphuric -S-esters as rubber/metal bonding promoters | MONSANTO EUROPE S.A./N.V. (BE) | 1985-07-31 | — | — | EP | disclosed |