SCHEMBL9861017

SCHEMBL9861017

C=Cc1ccc(C(C)CCCCCC)cc1.C=Cc1ccccc1Cl

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.45
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
CSNK1E P49674 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
TAS1R3 Q7RTX0 1/20 0.31
TAS1R1 Q7RTX1 1/20 0.31
CYP1A1 P04798 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP1B1 Q16678 1/20 0.31
RELA Q04206 1/20 0.31
NFE2L2 Q16236 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28901186 0.85 TAS1R3 (0.39) ALDH1A1LMNACSNK1EMEN1KMT2A
SCHEMBL9838748 0.85 TAS1R3 (0.39) ALDH1A1LMNACSNK1EMEN1KMT2A
SCHEMBL9838337 0.85 TAS1R3 (0.39) ALDH1A1LMNACSNK1EMEN1KMT2A
SCHEMBL9717991 0.85 TAS1R3 (0.39) ALDH1A1LMNACSNK1EMEN1KMT2A
SCHEMBL9717972 0.84 TAS1R3 (0.40) ALDH1A1TAS1R3TAS1R1CA1CA2
SCHEMBL2778094 0.79 ALDH1A1 (0.41) ALDH1A1TAS1R3TAS1R1CA1CA2
Pentane SCHEMBL27715496 0.76 ALDH1A1 (0.72) ALDH1A1KDM4ELMNACYP1A1CYP1A2
SCHEMBL29183951 0.74 CSNK1E (0.41) ALDH1A1CSNK1EMEN1KMT2ANPSR1
SCHEMBL5024850 0.73 TAS1R3 (0.46) ALDH1A1LMNATAS1R3TAS1R1
SCHEMBL9137197 0.72 SLC2A1 (0.44) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4994515-A Resin of styrene and unsaturated imide, high impact thermoplastic, bromine-containing reaction product, silicon resin or compound SHOWA DENKO KABUSHIKI KAISHA (JP) 1991-02-19 US disclosed