Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | MDH1 | P40925 | 3/20 | 0.36 |
| ▸ | MDH2 | P40926 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9860969 | 0.85 | NR4A2 (0.45) | SMN1; SMN2KMT2ACA2CA9MEN1 | |
| SCHEMBL22939515 | 0.82 | SHBG (0.52) | SHBGCYP3A4SMN1; SMN2KMT2AESR1 | |
| SCHEMBL10501977 | 0.81 | CA2 (0.54) | CYP3A4KMT2ACA2CA9CA1 | |
| SCHEMBL29105129 | 0.79 | KMT2A (0.65) | KMT2ACA2CA9CA1 | |
| SCHEMBL9861023 | 0.76 | CA2 (0.61) | KMT2ACA2CA9CA1 | |
| SCHEMBL9861765 | 0.76 | CA2 (0.45) | SMN1; SMN2KMT2ACA2CA9CA1 | |
| SCHEMBL8355093 | 0.75 | SHBG (0.55) | SHBGCYP3A4SMN1; SMN2KMT2AESR1 | |
| SCHEMBL9861747 | 0.73 | IDO1 (0.53) | SMN1; SMN2APP | |
| SCHEMBL9861407 | 0.73 | CA2 (0.46) | SMN1; SMN2ESR1ESR2CA2CA9 | |
| SCHEMBL10859327 | 0.73 | IDO1 (0.50) | KMT2ACA2CA9CA1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150168-B1 | USE OF METAL SALTS OF THIOSULPHURIC -S-ESTERS AS RUBBER/METAL BONDING PROMOTERS | MONSANTO EUROPE S.A./N.V. (BE) | 1991-05-08 | — | — | EP | disclosed |
| US-4581297-A | STEEL BELTED RADIAL TIRES | MONSANTO EUROPE, S.A. (BE) | 1986-04-08 | — | — | US | disclosed |
| EP-0150168-A2 | Use of metal salts of thiosulphuric -S-esters as rubber/metal bonding promoters | MONSANTO EUROPE S.A./N.V. (BE) | 1985-07-31 | — | — | EP | disclosed |