SCHEMBL9861200

SCHEMBL9861200

CC1CCC(C(C)C)C(OCC=O)C1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.58
LMNA P02545 2/20 0.48
KDM4E B2RXH2 1/20 0.46
APOBEC3A P31941 1/20 0.46
APOBEC3G Q9HC16 1/20 0.46
P2RX4 Q99571 1/20 0.45
GAA P10253 1/20 0.45
EPHX1 P07099 3/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
CYP19A1 P11511 2/20 0.43
TRPA1 O75762 2/20 0.43
TRPM8 Q7Z2W7 2/20 0.43
MAPT P10636 1/20 0.43
NFE2L2 Q16236 1/20 0.43
NTSR1 P30989 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
HPGD P15428 1/20 0.41
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15829156 1.00 ALDH1A1 (0.58) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL6139544 0.85 ALDH1A1 (0.56) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL21130372 0.85 ALDH1A1 (0.56) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL18230878 0.85 ALDH1A1 (0.56) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL6360423 0.85 ALDH1A1 (0.56) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL6355040 0.85 ALDH1A1 (0.56) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL29306795 0.85 ALDH1A1 (0.56) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL1400917 0.83 ALDH1A1 (0.63) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL8070812 0.82 ALDH1A1 (0.75) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G
SCHEMBL10519642 0.82 ALDH1A1 (0.65) ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0413068-A1 Process for making an optically active mixture of an n-acyl-amino acid or ester containing at least two chiral centers THE STANDARD OIL COMPANY (US) 1991-02-20 EP disclosed