Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29306795 | 1.00 | ALDH1A1 (0.56) | ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL21130372 | 1.00 | ALDH1A1 (0.56) | ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL6355040 | 1.00 | ALDH1A1 (0.56) | ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL6360423 | 1.00 | ALDH1A1 (0.56) | ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL18230878 | 1.00 | ALDH1A1 (0.56) | ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL15829156 | 0.85 | ALDH1A1 (0.58) | ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL9861200 | 0.85 | ALDH1A1 (0.58) | ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL7793171 | 0.84 | ALDH1A1 (0.61) | ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL6353084 | 0.84 | ALDH1A1 (0.61) | ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL10686198 | 0.81 | ALDH1A1 (0.61) | ALDH1A1LMNAKDM4EAPOBEC3AAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1253130-B1 | Method for producing 3-l-menthoxypropane-1,2-diol | TAKASAGO PERFUMERY CO LTD (JP) | 2005-11-02 | — | — | EP | disclosed |
| US-6515188-B2 | Reacting l-menthol with 1,2-epoxy-3-halogenopropane in an organic solvent and Lewis acid, the product is reacted with a alkali metal salt of a carboxyalkyl acid, followed by hydrolysis | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2003-02-04 | — | — | US | disclosed |
| EP-1253130-A2 | Method for producing 3-l-menthoxypropane-1,2-diol | Takasago International Corporation (JP) | 2002-10-30 | — | — | EP | disclosed |
| US-20020156327-A1 | Method for producing 3-l-menthoxypropane-1,2-diol | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-10-24 | — | — | US | disclosed |
| US-20020077367-A1 | PROCESS FOR PRODUCING 3-L-MENTHOXYPROPANE-1,2-DIOL | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-06-20 | — | — | US | disclosed |
| EP-1201635-A1 | Process for producing 3-l-menthoxypropane-1,2-diol | Takasago International Corporation (JP) | 2002-05-02 | — | — | EP | disclosed |
| US-5608119-A | (2S)-3-[(1R, 2S, 5R)-[5-methyl-2-(1-methylethyl)-cyclohexyl]oxy]-1, 2-propanediol, process for producing the same, and compositions containing the same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1997-03-04 | — | — | US | disclosed |
| US-4459425-A | PHYSIOLOGICAL COOLANTS | TAKASAGO PERFUMERY CO., LTD. (JP) | 1984-07-10 | — | — | US | disclosed |
| EP-0080148-A1 | 3-l-menthoxypropane-1,2-Diol | Takasago Perfumery Co., Ltd. (JP) | 1983-06-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020156327-A1 | Method for producing 3-l-menthoxypropane-1,2-diol | LOXL2, FAAH2, LOXL1 | ALDH1A1 59/4885LMNA 2536/4885KDM4E 1229/4885 |
| US-20020077367-A1 | PROCESS FOR PRODUCING 3-L-MENTHOXYPROPANE-1,2-DIOL | LOXL1, LOXL2, LOX | ALDH1A1 28/4885LMNA 2191/4885KDM4E 949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.