Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.41 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.41 |
| ▸ | IAPP | P10997 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1094265 | 0.90 | AKR1C3 (0.48) | ERN1AKR1C3TRIM24TRIM33CA1 | |
| SCHEMBL3422780 | 0.90 | AKR1C3 (0.48) | ERN1AKR1C3TRIM24TRIM33CA1 | |
| SCHEMBL8746654 | 0.78 | AKR1C3 (0.55) | AKR1C3APEX1KDM4E | |
| SCHEMBL8746657 | 0.78 | AKR1C3 (0.55) | AKR1C3APEX1KDM4E | |
| SCHEMBL1563517 | 0.77 | ERN1 (0.57) | ERN1AKR1C3CA1CA2IAPP | |
| SCHEMBL691674 | 0.77 | ERN1 (0.57) | ERN1AKR1C3CA1CA2IAPP | |
| SCHEMBL8416364 | 0.77 | AKR1C3 (0.59) | ERN1AKR1C3TRIM24TRIM33LMNA | |
| SCHEMBL7525200 | 0.77 | AKR1C3 (0.59) | ERN1AKR1C3TRIM24TRIM33LMNA | |
| SCHEMBL208434 | 0.77 | AKR1C3 (0.59) | AKR1C3TRIM24TRIM33CA1CA2 | |
| SCHEMBL1137305 | 0.77 | AKR1C3 (0.59) | AKR1C3TRIM24TRIM33CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266548-B1 | USE OF POLYMERISABLE MIXTURES FOR THE MANUFACTURE OF ADHESIVE PRODUCTS FOR BIOLOGICAL SUBSTRATES BASED ON COMPOUNDS CONSISTING OF ALDEHYDE, EPOXIDE, ISOCYANATE OR HALOTRIAZINE GROUPS, POLYMERIZABLE GROUPS AND A HIGHER MOLECULAR-WEIGHT BACKBONE | Ernst Mühlbauer KG (DE) | 1991-09-04 | — | — | EP | disclosed |
| EP-0266548-A1 | Use of polymerisable mixtures for the manufacture of adhesive products for biological substrates based on compounds consisting of aldehyde, epoxide, isocyanate or halotriazine groups, polymerizable groups and a higher molecular-weight backbone | Ernst Mühlbauer KG (DE) | 1988-05-11 | — | — | EP | disclosed |