Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5062317 | 1.00 | ALDH1A1 (0.53) | ALDH1A1MAPTHPGDGAAPTPN2 | |
| SCHEMBL27622256 | 0.78 | PTPN2 (0.50) | ALDH1A1MAPTHPGDGAAPTPN2 | |
| SCHEMBL27182236 | 0.76 | L3MBTL1 (0.71) | ALDH1A1MAPTHPGDGAASMN1; SMN2 | |
| SCHEMBL10971455 | 0.75 | PTPN2 (0.49) | ALDH1A1MAPTHPGDGAAPTPN2 | |
| SCHEMBL3909838 | 0.75 | ALDH1A1 (0.55) | ALDH1A1MAPTHPGDGAASMN1; SMN2 | |
| SCHEMBL28988328 | 0.74 | ALDH1A1 (0.48) | ALDH1A1MAPTHPGDSMN1; SMN2MEN1 | |
| SCHEMBL7648958 | 0.74 | CYP3A4 (0.61) | GAAPTPN2PTPN1PTPN6PTPN11 | |
| SCHEMBL6427641 | 0.74 | CYP3A4 (0.61) | GAAPTPN2PTPN1PTPN6PTPN11 | |
| SCHEMBL10590844 | 0.74 | MEN1 (0.50) | ALDH1A1MAPTHPGDGAAPTPN2 | |
| SCHEMBL13539432 | 0.73 | L3MBTL1 (0.73) | ALDH1A1MAPTHPGDGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011875-A | Ethylene-propylene terpolymer, water absorbent, and corrosion inhibitor; useds for gaskets, sealants and caulking material | HIROSHIMA KASEI LTD. (JP) | 1991-04-30 | — | — | US | disclosed |