Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9861500 | 0.80 | CYP1A2 (0.51) | LMNANPC1RAB9AGAATP53 | |
| SCHEMBL9861753 | 0.77 | BCHE (0.49) | SMN1; SMN2HTTTP53ALDH1A1TSHR | |
| SCHEMBL9861771 | 0.74 | IDO1 (0.43) | TDP1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9861031 | 0.74 | BCHE (0.44) | GAAHTTALDH1A1 | |
| SCHEMBL9861684 | 0.73 | MAPK1 (0.50) | MAPK1EPHX2TDP1LMNASMN1; SMN2 | |
| SCHEMBL6947559 | 0.73 | MAPK1 (0.57) | MAPK1EPHX2TDP1SMN1; SMN2S1PR1 | |
| 1,4-Diisopentoxybenzene SCHEMBL2846102 | 0.73 | TDP1 (0.79) | MAPK1EPHX2TDP1LMNASMN1; SMN2 | |
| SCHEMBL12317755 | 0.72 | TDP1 (0.58) | MAPK1EPHX2TDP1LMNASMN1; SMN2 | |
| SCHEMBL9861353 | 0.72 | MAPK1 (0.37) | MAPK1EPHX2TDP1SMN1; SMN2RAB9A | |
| SCHEMBL9820054 | 0.72 | TDP1 (0.61) | MAPK1EPHX2TDP1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150168-B1 | USE OF METAL SALTS OF THIOSULPHURIC -S-ESTERS AS RUBBER/METAL BONDING PROMOTERS | MONSANTO EUROPE S.A./N.V. (BE) | 1991-05-08 | — | — | EP | disclosed |
| US-4581297-A | STEEL BELTED RADIAL TIRES | MONSANTO EUROPE, S.A. (BE) | 1986-04-08 | — | — | US | disclosed |
| EP-0150168-A2 | Use of metal salts of thiosulphuric -S-esters as rubber/metal bonding promoters | MONSANTO EUROPE S.A./N.V. (BE) | 1985-07-31 | — | — | EP | disclosed |