SCHEMBL9861771

SCHEMBL9861771

CCc1ccc(CSOS(=O)(=O)O)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.43
CA2 P00918 2/20 0.41
LPL P06858 1/20 0.39
LIPG Q9Y5X9 1/20 0.39
ALDH1A1 P00352 4/20 0.38
EGFR P00533 1/20 0.38
DAO P14920 1/20 0.36
HPGD P15428 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
CYP2C19 P33261 1/20 0.36
GPR84 Q9NQS5 1/20 0.36
PLK1 P53350 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
UCHL1 P09936 1/20 0.34
KDM4E B2RXH2 1/20 0.33
F2 P00734 1/20 0.33
MAPT P10636 1/20 0.33
VDR P11473 1/20 0.33
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9861031 0.85 BCHE (0.44) IDO1CA2ALDH1A1MAPT
SCHEMBL9861753 0.82 BCHE (0.49) IDO1CA2ALDH1A1DAOSMN1; SMN2
SCHEMBL9860936 0.82 TRPA1 (0.34) IDO1CA2LPLLIPGALDH1A1
SCHEMBL10859332 0.81 IDO1 (0.43) IDO1CA2EGFRDAOLMNA
SCHEMBL5078812 0.81 CYP2C19 (0.40) IDO1CA2ALDH1A1SMN1; SMN2CYP2C19
SCHEMBL9861383 0.81 BCHE (0.41) IDO1CA2ALDH1A1HPGDLMNA
SCHEMBL9860976 0.81 BCHE (0.48) CA2ALDH1A1DAORXRARXRB
SCHEMBL10709455 0.79 CYP2C19 (0.39) IDO1CA2ALDH1A1CYP2C19KDM4E
SCHEMBL9861500 0.78 CYP1A2 (0.51) ALDH1A1CYP2C19KDM4EMAPTLMNA
SCHEMBL28736653 0.77 IDO1 (0.47) IDO1CA2DAOMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0150168-B1 USE OF METAL SALTS OF THIOSULPHURIC -S-ESTERS AS RUBBER/METAL BONDING PROMOTERS MONSANTO EUROPE S.A./N.V. (BE) 1991-05-08 EP disclosed
US-4581297-A STEEL BELTED RADIAL TIRES MONSANTO EUROPE, S.A. (BE) 1986-04-08 US disclosed
EP-0150168-A2 Use of metal salts of thiosulphuric -S-esters as rubber/metal bonding promoters MONSANTO EUROPE S.A./N.V. (BE) 1985-07-31 EP disclosed