Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9861492 | 0.79 | POLB (0.50) | TDP1GAATP53ALDH1A1NPC1 | |
| SCHEMBL10501977 | 0.78 | CA2 (0.54) | — | |
| SCHEMBL9861747 | 0.77 | IDO1 (0.53) | GAAHTTSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL9861349 | 0.74 | MAPK1 (0.40) | MAPK1EPHX2TDP1HTTSMN1; SMN2 | |
| SCHEMBL6947559 | 0.74 | MAPK1 (0.57) | MAPK1EPHX2TDP1S1PR1S1PR5 | |
| SCHEMBL5081935 | 0.74 | CA1 (0.40) | MAPK1EPHX2TDP1HTTTP53 | |
| 1,4-Diisopentoxybenzene SCHEMBL2846102 | 0.74 | TDP1 (0.79) | MAPK1EPHX2TDP1S1PR1S1PR5 | |
| SCHEMBL9861692 | 0.73 | MAPK1 (0.49) | MAPK1EPHX2TDP1S1PR1S1PR5 | |
| SCHEMBL9861023 | 0.73 | CA2 (0.61) | MAPK1GAAALDH1A1NPC1LMNA | |
| SCHEMBL9861765 | 0.73 | CA2 (0.45) | TDP1SMN1; SMN2ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150168-B1 | USE OF METAL SALTS OF THIOSULPHURIC -S-ESTERS AS RUBBER/METAL BONDING PROMOTERS | MONSANTO EUROPE S.A./N.V. (BE) | 1991-05-08 | — | — | EP | disclosed |
| US-4581297-A | STEEL BELTED RADIAL TIRES | MONSANTO EUROPE, S.A. (BE) | 1986-04-08 | — | — | US | disclosed |
| EP-0150168-A2 | Use of metal salts of thiosulphuric -S-esters as rubber/metal bonding promoters | MONSANTO EUROPE S.A./N.V. (BE) | 1985-07-31 | — | — | EP | disclosed |