Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 8/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.48 |
| ▸ | GLS | O94925 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9861110 | 0.89 | SMN1; SMN2 (0.56) | SMN1; SMN2RAB9AMAPTTDP1 | |
| SCHEMBL9860919 | 0.89 | MAPT (0.53) | SMN1; SMN2HPGDNPSR1RAB9ATSHR | |
| SCHEMBL14015387 | 0.88 | SMN1; SMN2 (0.54) | SMN1; SMN2HPGDNPSR1RAB9ANPC1 | |
| SCHEMBL9861057 | 0.88 | MAPT (0.51) | SMN1; SMN2HPGDNPSR1RAB9ATSHR | |
| SCHEMBL9861151 | 0.88 | SMN1; SMN2 (0.51) | SMN1; SMN2HPGDNPSR1RAB9ATSHR | |
| SCHEMBL19133388 | 0.86 | SMN1; SMN2 (0.50) | SMN1; SMN2HPGDNPSR1RAB9ATSHR | |
| SCHEMBL9861741 | 0.85 | CA12 (0.44) | HPGDTSHRMAPTGLSALDH1A1 | |
| SCHEMBL6716400 | 0.81 | HPGD (0.55) | SMN1; SMN2HPGDNPSR1RAB9ANPC1 | |
| SCHEMBL16997484 | 0.79 | HPGD (0.54) | SMN1; SMN2HPGDNPSR1RAB9ANPC1 | |
| SCHEMBL290900 | 0.78 | RAB9A (0.50) | SMN1; SMN2HPGDNPSR1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150168-B1 | USE OF METAL SALTS OF THIOSULPHURIC -S-ESTERS AS RUBBER/METAL BONDING PROMOTERS | MONSANTO EUROPE S.A./N.V. (BE) | 1991-05-08 | — | — | EP | disclosed |
| US-4581297-A | STEEL BELTED RADIAL TIRES | MONSANTO EUROPE, S.A. (BE) | 1986-04-08 | — | — | US | disclosed |
| EP-0150168-A2 | Use of metal salts of thiosulphuric -S-esters as rubber/metal bonding promoters | MONSANTO EUROPE S.A./N.V. (BE) | 1985-07-31 | — | — | EP | disclosed |