Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETDB1 | Q15047 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14204990 | 0.90 | SETDB1 (0.59) | SETDB1MTNR1ARAB9ANPC1NPSR1 | |
| SCHEMBL14651452 | 0.84 | SETDB1 (0.54) | SETDB1MTNR1ARAB9ANPC1NPSR1 | |
| SCHEMBL5987986 | 0.83 | MTNR1A (0.63) | MTNR1AMTNR1BNQO2L3MBTL1KMT2A | |
| SCHEMBL29675775 | 0.82 | SETDB1 (0.53) | SETDB1MTNR1ARAB9ANPC1NPSR1 | |
| SCHEMBL5988698 | 0.81 | MTNR1A (0.56) | MTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL1433979 | 0.81 | NPC1 (0.72) | RAB9ANPC1ALDH1A1POLBHTT | |
| SCHEMBL17123628 | 0.81 | SETDB1 (0.51) | SETDB1MTNR1ARAB9ANPC1NPSR1 | |
| SCHEMBL1799028 | 0.81 | SETDB1 (0.51) | SETDB1MTNR1ARAB9ANPC1NPSR1 | |
| SCHEMBL10781973 | 0.81 | SETDB1 (0.51) | SETDB1MTNR1ARAB9ANPC1NPSR1 | |
| SCHEMBL15030741 | 0.81 | SETDB1 (0.51) | SETDB1MTNR1ARAB9ANPC1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992588-A | Preparation of o-acylaminomethylbenzyl halides | BASF AKTIENGESELLSCHAFT (DE) | 1991-02-12 | — | — | US | disclosed |
| EP-0087676-B1 | PROCESS FOR THE PREPARATION OF O-ACYLAMINOMETHYLBENZYL HALOGENIDES | BASF Aktiengesellschaft (DE) | 1987-12-16 | — | — | EP | disclosed |
| EP-0087676-A1 | Process for the preparation of o-acylaminomethylbenzyl halogenides | BASF Aktiengesellschaft (DE) | 1983-09-07 | — | — | EP | disclosed |