Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.64 |
| ▸ | LMNA | P02545 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.64 |
| ▸ | MITF | O75030 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | CCR6 | P51684 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17249965 | 0.80 | MAPT (1.00) | MAPTLMNAALDH1A1TDP1MITF | |
| SCHEMBL1101039 | 0.75 | MAPT (0.46) | MAPTLMNAALDH1A1TDP1MITF | |
| SCHEMBL21141272 | 0.70 | CDC25A (0.47) | MAPTLMNAALDH1A1TDP1MITF | |
| SCHEMBL5160930 | 0.69 | MAPT (0.48) | MAPTLMNAALDH1A1TDP1MITF | |
| SCHEMBL15630257 | 0.66 | CDC25A (0.64) | MAPTLMNAALDH1A1TDP1MITF | |
| SCHEMBL10740378 | 0.63 | ALDH1A1 (0.58) | MAPTLMNAALDH1A1MAPK1NPSR1 | |
| SCHEMBL9560535 | 0.63 | RAB9A (0.49) | MAPTLMNAALDH1A1TDP1MITF | |
| SCHEMBL10793727 | 0.62 | NSD2 (0.53) | MAPTLMNAALDH1A1TDP1MITF | |
| SCHEMBL9701136 | 0.62 | HSP90AA1 (0.66) | MAPTLMNAALDH1A1HTTMAPK1 | |
| SCHEMBL27883899 | 0.61 | MAPT (0.53) | MAPTLMNAALDH1A1TDP1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0246112-B1 | PREPARATION OF DIAMINO- AND DIALKYLAMINOBENZENEDIOLS | THE DOW CHEMICAL COMPANY (US) | 1991-06-12 | — | — | EP | disclosed |
| US-4882267-A | SULFONAMIDE NON-COLOR-FORMING COMPOUND, HIGH BOILING PHOSPHATE SOLVENT, AMIDO-SUBSTITUTED PHENOLIC CYAN COUPLER | KONICA CORPORATION (JP) | 1989-11-21 | — | — | US | disclosed |
| EP-0324847-A1 | PREPARATION OF BIS (AMINE-CONTAINING) BENZENEDIOLS | THE DOW CHEMICAL COMPANY (US) | 1989-07-26 | — | — | EP | disclosed |
| US-4806688-A | Preparation of diamino- and dialkylaminobenzenediols | THE DOW CHEMICAL COMPANY (US) | 1989-02-21 | — | — | US | disclosed |
| EP-0246112-A1 | Preparation of diamino- and dialkylaminobenzenediols | THE DOW CHEMICAL COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |
| WO-1987006930-A1 | PREPARATION OF DIAMINO- AND DIALKYLAMINOBENZENEDIOLS | THE DOW CHEMICAL COMPANY (US) | 1987-11-19 | — | — | WO | disclosed |