Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 19/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9861622 | 0.73 | PDK2 (0.76) | PDK2 | |
| SCHEMBL9861418 | 0.70 | PDK2 (0.48) | PDK2 | |
| SCHEMBL9861282 | 0.68 | PDK2 (0.34) | PDK2 | |
| SCHEMBL8816141 | 0.67 | PDK2 (0.48) | PDK2 | |
| SCHEMBL9861506 | 0.66 | PDK2 (0.57) | PDK2 | |
| SCHEMBL20151671 | 0.66 | IDO1 (0.38) | — | |
| SCHEMBL4870136 | 0.66 | IDO1 (0.38) | — | |
| SCHEMBL11482321 | 0.65 | MEN1 (0.48) | PDK2 | |
| SCHEMBL15463143 | 0.64 | PDK2 (1.00) | PDK2 | |
| SCHEMBL31202620 | 0.63 | PDK2 (0.53) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5008425-A | Trifluoromethylation of carbonyl compounds | ETHYL CORPORATION (US) | 1991-04-16 | — | — | US | disclosed |
| US-4871877-A | Gem-disubstituted cyclohexadienones and their production | ETHYL CORPORATION (US) | 1989-10-03 | — | — | US | disclosed |