Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | TST | Q16762 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11481755 | 0.71 | ALDH1A1 (0.46) | ALDH1A1KMT2ALMNACYP1A2CYP3A4 | |
| SCHEMBL14303958 | 0.69 | — | — | |
| SCHEMBL20151671 | 0.67 | IDO1 (0.38) | IDO1ALDH1A1KMT2ALMNACYP1A2 | |
| SCHEMBL9861969 | 0.66 | PDK2 (0.46) | — | |
| SCHEMBL11488102 | 0.65 | MEN1 (0.54) | ALDH1A1KMT2ALMNACYP1A2CYP3A4 | |
| SCHEMBL8946994 | 0.64 | KMT2A (0.31) | KMT2A | |
| SCHEMBL29522682 | 0.61 | MEN1 (0.52) | ALDH1A1KMT2ALMNACYP1A2CYP3A4 | |
| SCHEMBL12997896 | 0.61 | MEN1 (0.52) | ALDH1A1KMT2ALMNACYP1A2CYP3A4 | |
| SCHEMBL16532992 | 0.61 | USP8 (0.49) | ALDH1A1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL1855552 | 0.61 | MEN1 (0.52) | ALDH1A1KMT2ALMNACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8969249-B2 | Synthesis and biological activity of bicyclic ABA analogs | NATIONAL RESEARCH COUNCIL OF CANADA | 2015-03-03 | — | — | US | claimed |
| US-20080200339-A1 | Methylating 1-tetralone to produce dimethyl tetralone or reacting 2-methyl-1-naphthol, alkylating with 3-methylpent-2-en-4-yn-1-ol, oxidizing the alcohol to an ester, reacting the ester or deprotecting the ketal to give a ketone; inhibiting cell growth and seed germination; herbicides | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2008-08-21 | — | — | US | claimed |
| WO-2005108345-A1 | SYNTHESIS AND BIOLOGICAL ACTIVITY OR NOVEL BICYCLIC ABA ANALOGS | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2005-11-17 | — | — | WO | claimed |
| US-8969249-B2 | Synthesis and biological activity of bicyclic ABA analogs | NATIONAL RESEARCH COUNCIL OF CANADA | 2015-03-03 | — | — | US | disclosed |
| US-8969249-B2 | Synthesis and biological activity of bicyclic ABA analogs | NATIONAL RESEARCH COUNCIL OF CANADA | 2015-03-03 | — | — | US | disclosed |
| US-20080200339-A1 | Methylating 1-tetralone to produce dimethyl tetralone or reacting 2-methyl-1-naphthol, alkylating with 3-methylpent-2-en-4-yn-1-ol, oxidizing the alcohol to an ester, reacting the ester or deprotecting the ketal to give a ketone; inhibiting cell growth and seed germination; herbicides | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2008-08-21 | — | — | US | disclosed |
| US-20080200339-A1 | Methylating 1-tetralone to produce dimethyl tetralone or reacting 2-methyl-1-naphthol, alkylating with 3-methylpent-2-en-4-yn-1-ol, oxidizing the alcohol to an ester, reacting the ester or deprotecting the ketal to give a ketone; inhibiting cell growth and seed germination; herbicides | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2008-08-21 | — | — | US | disclosed |
| WO-2005108345-A1 | SYNTHESIS AND BIOLOGICAL ACTIVITY OR NOVEL BICYCLIC ABA ANALOGS | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2005-11-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200339-A1 | Methylating 1-tetralone to produce dimethyl tetralone or reacting 2-methyl-1-naphthol, alkylating with 3-methylpent-2-en-4-yn-1-ol, oxidizing the alcohol to an ester, reacting the ester or deprotecting the ketal to give a ketone; inhibiting cell growth and seed germination; herbicides | FASN, HACL2, ACSL1 | IDO1 1270/4885ALDH1A1 435/4885KMT2A 163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.