Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETDB1 | Q15047 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.44 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14204990 | 0.87 | SETDB1 (0.59) | SETDB1MTNR1AMTNR1BNPSR1HPGD | |
| SCHEMBL3918538 | 0.86 | HPGD (0.47) | NPSR1CACNA1GCACNA1HCACNA1IHPGD | |
| SCHEMBL15716617 | 0.84 | NPSR1 (0.44) | MTNR1AMTNR1BNPSR1CACNA1GCACNA1H | |
| SCHEMBL14651452 | 0.81 | SETDB1 (0.54) | SETDB1MTNR1AMTNR1BNPSR1HPGD | |
| SCHEMBL14651456 | 0.80 | SETDB1 (0.44) | SETDB1MTNR1AMTNR1BNPSR1HPGD | |
| SCHEMBL29675775 | 0.79 | SETDB1 (0.53) | SETDB1MTNR1AMTNR1BNPSR1HPGD | |
| SCHEMBL31531439 | 0.79 | KMT2A (0.45) | NPSR1CACNA1GCACNA1HCACNA1IHPGD | |
| SCHEMBL10781979 | 0.79 | SETDB1 (0.49) | SETDB1MTNR1AMTNR1BNPSR1HPGD | |
| SCHEMBL885000 | 0.79 | MTNR1A (0.71) | MTNR1AMTNR1BNPSR1HPGDKMT2A | |
| SCHEMBL1799028 | 0.78 | SETDB1 (0.51) | SETDB1MTNR1AMTNR1BNPSR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108617166-B | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-05-17 | — | — | CN | claimed |
| US-4992588-A | Preparation of o-acylaminomethylbenzyl halides | BASF AKTIENGESELLSCHAFT (DE) | 1991-02-12 | — | — | US | disclosed |
| EP-0087676-B1 | PROCESS FOR THE PREPARATION OF O-ACYLAMINOMETHYLBENZYL HALOGENIDES | BASF Aktiengesellschaft (DE) | 1987-12-16 | — | — | EP | disclosed |
| EP-0087676-A1 | Process for the preparation of o-acylaminomethylbenzyl halogenides | BASF Aktiengesellschaft (DE) | 1983-09-07 | — | — | EP | disclosed |