SCHEMBL9862013

SCHEMBL9862013

Cc1cnc(OC(=O)O)c(Cl)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SSTR4 P31391 1/20 0.41
POLB P06746 1/20 0.37
LIPE Q05469 4/20 0.36
SLC13A5 Q86YT5 3/20 0.36
SLC13A2 Q13183 1/20 0.36
SLC13A3 Q8WWT9 1/20 0.36
RORC P51449 1/20 0.36
HCAR2 Q8TDS4 1/20 0.35
DRD1 P21728 1/20 0.35
LMNA P02545 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
TRPM8 Q7Z2W7 1/20 0.34
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
CYP2C9 P11712 1/20 0.33
TSHR P16473 1/20 0.33
APEX1 P27695 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8099529 0.80 SMN1; SMN2 (0.38) LIPERORCLMNAL3MBTL1ALDH1A1
SCHEMBL3837299 0.80 SLC13A5 (0.37) SLC13A5SLC13A2SLC13A3HCAR2KDM4E
SCHEMBL10435499 0.78 KMT2A (0.37) LIPERORCLMNAL3MBTL1KDM4E
SCHEMBL10435496 0.77 LMNA (0.41) LIPERORCLMNAL3MBTL1ALDH1A1
SCHEMBL5942263 0.75 CYP2C9 (0.42) SSTR4POLBSLC13A5SLC13A2SLC13A3
SCHEMBL29458513 0.75 CYP2C9 (0.42) SSTR4POLBSLC13A5SLC13A2SLC13A3
SCHEMBL10435189 0.75 SMN1; SMN2 (0.56) LIPELMNAALDH1A1RAB9ASMN1; SMN2
SCHEMBL10920276 0.72 KDM4E (0.44) POLBLMNAL3MBTL1KDM4EALDH1A1
SCHEMBL12037978 0.72 SLC13A5 (0.40) SSTR4SLC13A5RORCDRD1LMNA
SCHEMBL1105993 0.72 MEN1 (0.43) POLBHCAR2KDM4EALDH1A1TRPM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0428483-A1 Synergistic agent and method of selective weed control CIBA-GEIGY AG (CH) 1991-05-22 EP disclosed