SCHEMBL3837299

SCHEMBL3837299

Cc1cnc(OC(=O)O)c(OC(=O)O)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC13A5 Q86YT5 3/20 0.37
SLC13A2 Q13183 1/20 0.37
SLC13A3 Q8WWT9 1/20 0.37
HCAR2 Q8TDS4 1/20 0.36
TSHR P16473 1/20 0.33
ATM Q13315 1/20 0.33
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CYP2C9 P11712 1/20 0.32
PARP1 P09874 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
CCR1 P32246 1/20 0.31
CCR5 P51681 1/20 0.31
CCR8 P51685 1/20 0.31
NOS3 P29474 1/20 0.31
NOS1 P29475 1/20 0.31
NOS2 P35228 1/20 0.31
IKBKB O14920 1/20 0.31
PTGER4 P35408 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9862013 0.80 SSTR4 (0.41) SLC13A5SLC13A2SLC13A3HCAR2TSHR
SCHEMBL8566221 0.78 AGBL2 (0.38) HCAR2KDM4EPTGER4
SCHEMBL376878 0.77 PKM (0.37) TSHRALDH1A1KDM4ECYP2C9PARP1
SCHEMBL9838667 0.77 BCHE (0.33) HCAR2MAPT
SCHEMBL9838670 0.76 ATM (0.44) TSHRATMALDH1A1KDM4EHSD17B10
SCHEMBL9678280 0.76 CUL4A (0.40) SLC13A5SLC13A2SLC13A3ALDH1A1KDM4E
SCHEMBL7720520 0.75 NNMT (0.42) TSHRSMN1; SMN2NNMT
SCHEMBL9839366 0.75 SMN1; SMN2 (0.38) TSHRALDH1A1KDM4ESMN1; SMN2MAPT
SCHEMBL8649523 0.75 HCAR2 (0.34) HCAR2TSHRALDH1A1RAB9A
SCHEMBL9215105 0.73 SMN1; SMN2 (0.38) ALDH1A1KDM4ESMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3284847-B1 CORROSION INHIBITOR COMPOSITION FOR MAGNESIUM OR MAGNESIUM ALLOYS HELMHOLTZ ZENTRUM GEESTHACHT (DE) 2019-01-02 EP claimed
EP-1644333-B1 IN-SITU TREATMENT OF PYRIDINE-2,3-DICARBOXYLIC ACID ESTERS WITH AN OXIDIZING AGENT BASF SE (DE) 2009-09-23 EP claimed
EP-0503332-B1 Process for extracting pyridine and quinoline dicarboxylic acids from aqueous media AMERICAN CYANAMID CO (US) 1998-08-26 EP claimed
EP-0594993-B1 Method for the preparation of 2,3-pyridine-dicarboxylic acids and derivatives thereof AMERICAN CYANAMID CO (US) 1997-05-28 EP claimed
EP-0491140-B1 Method for the preparation of substituted and unsbustituted 2,3-pyridine and quinolinedicarboxylic acids AMERICAN CYANAMID CO (US) 1997-04-02 EP claimed
EP-0584470-B1 Process for the preparation of 2,3-pyridinedicarboxylic acids from 3-(2-imidazolin-2-yl)picolinic acids AMERICAN CYANAMID CO (US) 1995-08-16 EP claimed
EP-0331899-B1 A method for the sequential oxidation of substituted-8-hydroxy-quinolines to produce substituted-pyridine-2,3-dicarboxylic acids AMERICAN CYANAMID CO (US) 1994-04-27 EP claimed
EP-0259687-B1 METHOD FOR THE PREPARATION OF PYRIDINE-2,3-DICARBOXYLIC ACIDS AMERICAN CYANAMID COMPANY (US) 1991-07-03 EP claimed