SCHEMBL9862051

SCHEMBL9862051

Cc1ccc(C)c(C(=O)c2cc(C)ccc2C)c1

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
CSNK2A1 P68400 1/20 0.50
MAPK1 P28482 2/20 0.49
ALOX15 P16050 1/20 0.49
TSHR P16473 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.46
GAA P10253 1/20 0.45
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
HSD17B10 Q99714 1/20 0.44
KDM4E B2RXH2 1/20 0.43
NPC1 O15118 1/20 0.43
MAPT P10636 1/20 0.43
HTT P42858 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11611049 0.91 MEN1 (0.50) MEN1KMT2ACSNK2A1MAPK1ALOX15
SCHEMBL11610888 0.91 KMT2A (0.50) MEN1KMT2ACSNK2A1MAPK1ALOX15
SCHEMBL11753699 0.89 TSHR (0.51) MEN1KMT2ATSHRALDH1A1LMNA
SCHEMBL6057003 0.88 CSNK2A1 (0.55) MEN1KMT2ACSNK2A1MAPK1ALOX15
SCHEMBL9782367 0.87 ALDH1A1 (0.60) MEN1KMT2AMAPK1SMN1; SMN2GAA
SCHEMBL9420245 0.85 MEN1 (0.57) MEN1KMT2ACSNK2A1TSHRSMN1; SMN2
SCHEMBL7648043 0.84 AKR1C3 (0.61) MEN1KMT2ACSNK2A1ALOX15ALDH1A1
SCHEMBL11613043 0.84 KMT2A (0.45) MEN1KMT2AMAPK1ALOX15TSHR
SCHEMBL11947058 0.83 ALDH1A1 (0.59) MEN1KMT2AMAPK1SMN1; SMN2ALDH1A1
SCHEMBL305558 0.83 NPSR1 (0.60) MEN1KMT2AMAPK1GAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0032062-B2 HIGH-MOLECULAR-WEIGHT NOVOLAK SUBSTITUTED PHENOLIC RESINS AND THEIR PREPARATION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-10-16 EP disclosed
EP-0032062-B1 HIGH-MOLECULAR-WEIGHT NOVOLAK SUBSTITUTED PHENOLIC RESINS AND THEIR PREPARATION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1985-04-03 EP disclosed
US-4345054-A High-molecular-weight novolak types substituted phenolic resins and process for preparation thereof MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1982-08-17 US disclosed
EP-0032062-A2 High-molecular-weight novolak substituted phenolic resins and their preparation MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1981-07-15 EP disclosed
US-4071540-A MALEIC OR PHTHALIC CHEVRON RESEARCH COMPANY (US) 1978-01-31 US disclosed
US-4028481-A ACTIVATED TITANIUM TRICHLORIDE AND AN ORGANOALUMINUM COMPOUND MITSUI TOATSU CHEMICALS, INCORPORATED (JA) 1977-06-07 US disclosed