SCHEMBL7648043

SCHEMBL7648043

Cc1ccc(C)c(C(=O)c2ccccc2C(=O)O)c1

nearest known ligand 0.68

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 2/20 0.61
ALDH1A1 P00352 5/20 0.60
POLB P06746 1/20 0.60
KMT2A Q03164 3/20 0.57
CYP3A4 P08684 1/20 0.57
CYP2C9 P11712 1/20 0.57
CSNK2A1 P68400 1/20 0.52
ALOX15 P16050 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
MEN1 O00255 2/20 0.49
CDC25A P30304 1/20 0.49
CDC25B P30305 1/20 0.49
HSD17B10 Q99714 1/20 0.49
CYP1A2 P05177 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11753699 0.87 TSHR (0.51) ALDH1A1KMT2ACYP3A4CYP2C9NPSR1
SCHEMBL1787143 0.86 AKR1C3 (0.66) AKR1C3ALDH1A1POLBKMT2ACYP3A4
SCHEMBL6057003 0.85 CSNK2A1 (0.55) AKR1C3ALDH1A1POLBKMT2ACSNK2A1
SCHEMBL9862051 0.84 MEN1 (0.57) ALDH1A1KMT2ACSNK2A1ALOX15MEN1
SCHEMBL7849103 0.84 NPSR1 (0.46) AKR1C3ALDH1A1POLBKMT2ANPSR1
SCHEMBL9513995 0.84 ALDH1A1 (0.58) AKR1C3ALDH1A1POLBKMT2ACYP3A4
SCHEMBL1960435 0.84 CSNK2A1 (0.70) AKR1C3ALDH1A1POLBKMT2ACYP3A4
SCHEMBL29378415 0.83 KMT2A (0.68) AKR1C3ALDH1A1POLBKMT2ACYP3A4
SCHEMBL7001733 0.83 KMT2A (0.68) AKR1C3ALDH1A1POLBKMT2ACYP3A4
SCHEMBL357669 0.83 CYP3A4 (0.72) AKR1C3ALDH1A1POLBKMT2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6395077-B1 INKS WITH BENZOYLBENZOIC ACID AND COLORS XEROX CORPORATION 2002-05-28 US claimed
US-6395077-B1 INKS WITH BENZOYLBENZOIC ACID AND COLORS XEROX CORPORATION 2002-05-28 US disclosed
US-6328793-B1 FOR USE IN INK JET PRINTING PROCESSES, INCLUDING PIEZOELECTRIC INK JET PRINTING, ACOUSTIC INK JET PRINTING XEROX CORPORATION 2001-12-11 US disclosed
EP-1091958-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2001-04-18 EP disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 WO disclosed
US-5650399-A CONJUGATED WITH TARGET SPECIFIC OLIGONUCLEOTIDE, ACTIVATED BY LIGHT OR CHEMICAL/ENZYMATIC REDUCTION, ALKYLATION AND CROSSLINKING OF BIOLOGICAL MOLECULES SUCH DNA, ANTITUMOR THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1997-07-22 US disclosed
US-5057590-A Bislactone curing agents for epoxy resins and polymers obtained therefrom THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1991-10-15 US disclosed
US-4058529-A Polycyclic amino derivatives of pyrrolidone and piperidone CIBA-GEIGY CORPORATION (US) 1977-11-15 US disclosed