SCHEMBL9862097

SCHEMBL9862097

C#CC1C(C(=O)O)C1(C)C

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
APLNR P35414 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11460794 1.00 APLNR (0.37) APLNR
SCHEMBL11292944 1.00 APLNR (0.37) APLNR
Hydrochloric Acid SCHEMBL11288053 0.98 APLNR (0.36) APLNR
SCHEMBL11288048 0.81
SCHEMBL5246594 0.78 APLNR (0.41) APLNR
SCHEMBL3385056 0.78 APLNR (0.41) APLNR
SCHEMBL11260869 0.78 APLNR (0.41) APLNR
SCHEMBL29065423 0.75 APLNR (0.32) APLNR
SCHEMBL11140604 0.75 APLNR (0.32) APLNR
SCHEMBL11342420 0.73 APLNR (0.31) APLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0105006-B1 ALLENIC CYCLOPROPANE CARBOXYLATES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION, THEIR USE AS PARASITICIDES AND COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1986-03-19 EP claimed
US-4356187-A INSECTICIDES ROUSSEL UCLAF (FR) 1982-10-26 US claimed
EP-0018894-B1 ESTERS OF ALLETHROLONE DERIVATIVES AND CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION AND THE COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1982-02-17 EP claimed
EP-0018894-A1 Esters of allethrolone derivatives and carboxylic acids, process for their preparation and the compositions containing them ROUSSEL-UCLAF (FR) 1980-11-12 EP claimed
US-5004822-A Isomers of 3-acetyl-2,2-dimethyl cyclopropane carboxylic acid derivatives NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1991-04-02 US disclosed
US-4622337-A INSECTICIDES NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1986-11-11 US disclosed
EP-0105006-B1 ALLENIC CYCLOPROPANE CARBOXYLATES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION, THEIR USE AS PARASITICIDES AND COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1986-03-19 EP disclosed
US-4537897-A PESTICIDES ROUSSEL UCLAF (FR) 1985-08-27 US disclosed
US-4464391-A Pesticides NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1984-08-07 US disclosed
EP-0105006-A1 Allenic cyclopropane carboxylates, process and intermediates for their preparation, their use as parasiticides and compositions containing them ROUSSEL-UCLAF (FR) 1984-04-04 EP disclosed
US-4356187-A INSECTICIDES ROUSSEL UCLAF (FR) 1982-10-26 US disclosed
EP-0018894-B1 ESTERS OF ALLETHROLONE DERIVATIVES AND CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION AND THE COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1982-02-17 EP disclosed
EP-0018894-A1 Esters of allethrolone derivatives and carboxylic acids, process for their preparation and the compositions containing them ROUSSEL-UCLAF (FR) 1980-11-12 EP disclosed