Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL808904 | 1.00 | LMNA (0.50) | LMNATSHRCYP1A2CYP2C19TDP1 | |
| SCHEMBL10828300 | 1.00 | LMNA (0.50) | LMNATSHRCYP1A2CYP2C19TDP1 | |
| SCHEMBL7639324 | 0.87 | LMNA (0.49) | LMNATSHRCYP1A2CYP2C19TDP1 | |
| SCHEMBL809025 | 0.87 | LMNA (0.49) | LMNATSHRCYP1A2CYP2C19TDP1 | |
| SCHEMBL7633174 | 0.87 | LMNA (0.49) | LMNATSHRCYP1A2CYP2C19TDP1 | |
| SCHEMBL809024 | 0.87 | LMNA (0.49) | LMNATSHRCYP1A2CYP2C19TDP1 | |
| SCHEMBL808923 | 0.85 | LMNA (0.44) | LMNATSHRCYP1A2CYP2C19TDP1 | |
| SCHEMBL5706690 | 0.85 | LMNA (0.44) | LMNATSHRCYP1A2CYP2C19TDP1 | |
| SCHEMBL3358252 | 0.85 | LMNA (0.44) | LMNATSHRCYP1A2CYP2C19TDP1 | |
| SCHEMBL808827 | 0.85 | LMNA (0.44) | LMNATSHRCYP1A2CYP2C19TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5004822-A | Isomers of 3-acetyl-2,2-dimethyl cyclopropane carboxylic acid derivatives | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1991-04-02 | — | — | US | disclosed |
| US-4622337-A | INSECTICIDES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1986-11-11 | — | — | US | disclosed |