Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 3/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.36 |
| ▸ | LOX | P28300 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
| ▸ | THRA | P10827 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8388467 | 0.79 | LRRK2 (0.36) | PDGFRBPDGFRALOXLOXL2PTGS1 | |
| SCHEMBL10444786 | 0.79 | JAK3 (0.39) | PDGFRBPDGFRALOXLOXL2MCHR1 | |
| SCHEMBL11389109 | 0.74 | PDGFRB (0.36) | PDGFRBPDGFRALOXLOXL2PTGS1 | |
| SCHEMBL4784301 | 0.74 | PDGFRB (0.36) | PDGFRBPDGFRALOXLOXL2PTGS1 | |
| SCHEMBL19598395 | 0.74 | PDGFRB (0.36) | PDGFRBPDGFRALOXLOXL2PTGS1 | |
| SCHEMBL16691214 | 0.71 | HMOX1 (0.41) | PDGFRBPDGFRALOXLOXL2THRA | |
| SCHEMBL31426383 | 0.68 | PDGFRB (0.43) | PDGFRBPDGFRALOXLOXL2MCHR1 | |
| SCHEMBL164350 | 0.68 | HMOX1 (0.42) | PDGFRBPDGFRALOXLOXL2THRA | |
| SCHEMBL31581118 | 0.67 | MCHR1 (0.42) | PDGFRBPDGFRALOXLOXL2MCHR1 | |
| SCHEMBL9309427 | 0.67 | PDGFRB (0.41) | PDGFRBPDGFRALOXLOXL2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4981964-A | PHOTOSTABILIZERS | ICI AMERICAS INC. (US) | 1991-01-01 | — | — | US | disclosed |
| EP-0373839-A1 | Oligomeric polyesters and polyamides containing dipiperidyl triazine groups | ICI AMERICAS INC. (US) | 1990-06-20 | — | — | EP | disclosed |
| US-4889882-A | RADIATION RESISTANCE, PHOTOSTABILITY POLYMER ADDITIVE | ICI AMERICAS INC. (US) | 1989-12-26 | — | — | US | disclosed |