Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4650644 | 0.81 | KMT2A (0.62) | SMN1; SMN2PPARATSHRKMT2APPARG | |
| SCHEMBL8935639 | 0.81 | KMT2A (0.62) | SMN1; SMN2PPARATSHRKMT2APPARG | |
| SCHEMBL8326074 | 0.78 | GAA (0.50) | SMN1; SMN2PPARAMAPTTSHRLDHA | |
| SCHEMBL9862211 | 0.77 | KMT2A (0.66) | MAPTTDP1TSHRLDHAKDM4E | |
| SCHEMBL8386814 | 0.77 | LDHA (0.54) | SMN1; SMN2PPARALDHAPPARGACHE | |
| SCHEMBL2561624 | 0.77 | TSHR (0.49) | SMN1; SMN2PPARAMAPTTSHRKMT2A | |
| SCHEMBL4877555 | 0.76 | ALDH1A1 (0.57) | SMN1; SMN2MAPTTDP1TSHRKDM4E | |
| SCHEMBL6098435 | 0.76 | ALDH1A1 (0.47) | SMN1; SMN2KDM4EHSD17B10KMT2AMAPK1 | |
| SCHEMBL1565827 | 0.76 | PPARG (0.46) | SMN1; SMN2PPARATSHRKMT2APPARG | |
| SCHEMBL5707514 | 0.75 | TSHR (0.45) | SMN1; SMN2PPARATSHRKMT2APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045336-A | Reducing sweet taste of high sugar foods, organic acids and acid salts | AMSTAR SUGAR CORPORATION (US) | 1991-09-03 | — | — | US | disclosed |
| EP-0159864-B1 | METHOD OF MODIFYING TASTE | TATE & LYLE PUBLIC LIMITED COMPANY (GB) | 1989-07-19 | — | — | EP | disclosed |
| EP-0159864-A2 | Method of modifying taste | TATE & LYLE PUBLIC LIMITED COMPANY (GB) | 1985-10-30 | — | — | EP | disclosed |