Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.71 |
| ▸ | HTR1A | P08908 | 5/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.71 |
| ▸ | TSHR | P16473 | 2/20 | 0.71 |
| ▸ | PKM | P14618 | 1/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.70 |
| ▸ | GLA | P06280 | 1/20 | 0.70 |
| ▸ | APEX1 | P27695 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | FYN | P06241 | 1/20 | 0.68 |
| ▸ | DRD3 | P35462 | 5/20 | 0.61 |
| ▸ | HTR7 | P34969 | 4/20 | 0.61 |
| ▸ | DRD4 | P21917 | 3/20 | 0.61 |
| ▸ | DRD1 | P21728 | 2/20 | 0.61 |
| ▸ | HTR1D | P28221 | 2/20 | 0.61 |
| ▸ | DRD5 | P21918 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9424658 | 0.99 | LMNA (0.72) | DRD2HTR1ACYP1A2CYP2D6TSHR | |
| SCHEMBL14283976 | 0.90 | DRD2 (0.81) | DRD2HTR1ACYP1A2CYP2D6TSHR | |
| SCHEMBL5658541 | 0.83 | DRD2 (1.00) | DRD2HTR1ACYP1A2CYP2D6TSHR | |
| SCHEMBL29386657 | 0.83 | DRD2 (1.00) | DRD2HTR1ACYP1A2CYP2D6TSHR | |
| SCHEMBL5658545 | 0.83 | DRD2 (1.00) | DRD2HTR1ACYP1A2CYP2D6TSHR | |
| SCHEMBL7749343 | 0.83 | DRD2 (1.00) | DRD2HTR1ACYP1A2CYP2D6TSHR | |
| SCHEMBL15657500 | 0.83 | DRD2 (0.71) | DRD2HTR1ACYP1A2CYP2D6TSHR | |
| Bromide SCHEMBL29496166 | 0.82 | DRD2 (0.97) | DRD2HTR1ACYP1A2CYP2D6TSHR | |
| Bromide SCHEMBL9064205 | 0.82 | DRD2 (0.97) | DRD2HTR1ACYP1A2CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL5962618 | 0.82 | LMNA (1.00) | DRD2HTR1ACYP1A2CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991009006-A1 | NEW BICYCLIC AMINO-SUBSTITUTED COMPOUNDS | AKTIEBOLAGET ASTRA (SE) | 1991-06-27 | — | — | WO | disclosed |