Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PGR | P06401 | 6/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.46 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15085210 | 0.92 | HTT (0.52) | HTTTDP1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL24797471 | 0.89 | HTT (0.50) | HTTTDP1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL13884331 | 0.83 | HTT (0.56) | HTTTDP1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL8732460 | 0.83 | MTNR1B (0.46) | HTTSMN1; SMN2PGRALDH1A1MEN1 | |
| SCHEMBL18838829 | 0.83 | HTT (0.57) | HTTTDP1L3MBTL1SMN1; SMN2PGR | |
| SCHEMBL18905642 | 0.82 | APP (0.51) | HTTSMN1; SMN2LMNAALDH1A1MEN1 | |
| SCHEMBL8310971 | 0.81 | TSHR (0.52) | HTTSMN1; SMN2LMNAALDH1A1MEN1 | |
| SCHEMBL13228861 | 0.80 | APP (0.50) | HTTTDP1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL28630951 | 0.80 | LTA4H (0.55) | HTTSMN1; SMN2PGRALDH1A1MEN1 | |
| SCHEMBL27812196 | 0.80 | CACNA1B (0.48) | SMN1; SMN2PGRCACNA1BCACNA1HFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992575-A | Using disuccinyl imidomethylamine curing agent | AMERICAN CYANAMID COMPANY (US) | 1991-02-12 | — | — | US | disclosed |
| US-4778900-A | CURING AGENTS FOR EPOXY RESINS | AMERICAN CYANAMID COMPANY (US) | 1988-10-18 | — | — | US | disclosed |
| EP-0133281-A2 | Curable fibre reinforced epoxy resin composition | AMERICAN CYANAMID COMPANY (US) | 1985-02-20 | — | — | EP | disclosed |