Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 12/20 | 0.63 |
| ▸ | DRD3 | P35462 | 10/20 | 0.63 |
| ▸ | DRD4 | P21917 | 5/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | HTR5A | P47898 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 3/20 | 0.45 |
| ▸ | HTR1B | P28222 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9424993 | 0.99 | DRD2 (0.62) | DRD2DRD3DRD4MEN1CYP1A2 | |
| SCHEMBL9862345 | 0.84 | DRD2 (0.63) | DRD2DRD3DRD4MEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL9063936 | 0.83 | DRD2 (0.62) | DRD2DRD3DRD4MEN1CYP1A2 | |
| SCHEMBL9496955 | 0.83 | DRD2 (0.58) | DRD2DRD3DRD4MEN1CYP1A2 | |
| SCHEMBL7544212 | 0.79 | DRD2 (0.69) | DRD2DRD3DRD4CYP1A2 | |
| SCHEMBL7548060 | 0.79 | DRD2 (0.69) | DRD2DRD3DRD4CYP1A2 | |
| SCHEMBL2025137 | 0.78 | DRD2 (0.82) | DRD2DRD3DRD4CYP1A2HTR1D | |
| SCHEMBL2025960 | 0.78 | DRD2 (0.82) | DRD2DRD3DRD4CYP1A2HTR1D | |
| SCHEMBL2025138 | 0.78 | DRD2 (0.82) | DRD2DRD3DRD4CYP1A2HTR1D | |
| Hydrochloric Acid SCHEMBL7541435 | 0.77 | DRD2 (0.68) | DRD2DRD3DRD4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991009006-A1 | NEW BICYCLIC AMINO-SUBSTITUTED COMPOUNDS | AKTIEBOLAGET ASTRA (SE) | 1991-06-27 | — | — | WO | disclosed |