Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.58 |
| ▸ | DRD3 | P35462 | 7/20 | 0.58 |
| ▸ | DRD4 | P21917 | 3/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | HTR5A | P47898 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 2/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9862345 | 0.83 | DRD2 (0.63) | DRD2DRD3DRD4HTR1AMEN1 | |
| SCHEMBL9862396 | 0.83 | DRD2 (0.63) | DRD2DRD3DRD4HTR1AMEN1 | |
| Hydrochloric Acid SCHEMBL9424993 | 0.82 | DRD2 (0.62) | DRD2DRD3DRD4HTR1AMEN1 | |
| Hydrochloric Acid SCHEMBL9063936 | 0.82 | DRD2 (0.62) | DRD2DRD3DRD4HTR1AMEN1 | |
| SCHEMBL6052960 | 0.80 | HTR1A (0.52) | DRD2DRD3DRD4ADRA1AHTR1A | |
| SCHEMBL9532979 | 0.80 | MTNR1A (0.64) | DRD2DRD3DRD4MTNR1AMTNR1B | |
| SCHEMBL2025960 | 0.79 | DRD2 (0.82) | DRD2DRD3DRD4CYP1A2MTNR1A | |
| SCHEMBL2025137 | 0.79 | DRD2 (0.82) | DRD2DRD3DRD4CYP1A2MTNR1A | |
| SCHEMBL2025138 | 0.79 | DRD2 (0.82) | DRD2DRD3DRD4CYP1A2MTNR1A | |
| SCHEMBL8688541 | 0.79 | DRD2 (0.56) | DRD2DRD3DRD4HTR1ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532398-A1 | N-(4,7-dimethoxyindan-2-yle)-1-(phenylcarbonyl)-N-propyle-piperidine-4-methane amines, their preparation and their therapeutical application | SYNTHELABO (FR) | 1993-03-17 | — | — | EP | claimed |
| JP-5201978-A | — | — | None | — | — | JP | disclosed |
| JP-H05201978-A | N-(4,7-DIMETHOXY-2-INDANYL)-1-(PHENYLCARBONYL)-N-PROPYL-4-PIRERIDINE METHANEAMINE DERIVATIVE, ITS PREPARATION AND ITS APPLICATION TO PHARMACEUTICALS | SYNTHELABO SA | 1993-08-10 | — | — | JP | disclosed |
| EP-0532398-A1 | N-(4,7-dimethoxyindan-2-yle)-1-(phenylcarbonyl)-N-propyle-piperidine-4-methane amines, their preparation and their therapeutical application | SYNTHELABO (FR) | 1993-03-17 | — | — | EP | disclosed |