Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 10/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | VDR | P11473 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9862564 | 0.99 | FFAR1 (0.50) | FFAR1FFAR4CYP1A2KDM4ENPC1 | |
| SCHEMBL10451931 | 0.92 | FFAR1 (0.48) | FFAR1FFAR4CYP1A2KDM4ENPC1 | |
| SCHEMBL9862466 | 0.90 | PTGS1 (0.53) | FFAR1FFAR4CYP1A2KDM4ENPC1 | |
| SCHEMBL9862483 | 0.90 | PTGS1 (0.53) | FFAR1FFAR4CYP1A2KDM4ENPC1 | |
| SCHEMBL9862381 | 0.90 | ALDH1A1 (0.45) | FFAR1CYP1A2KDM4ELMNASMN1; SMN2 | |
| SCHEMBL9862577 | 0.90 | ALDH1A1 (0.45) | FFAR1CYP1A2KDM4ELMNASMN1; SMN2 | |
| SCHEMBL10452177 | 0.88 | FFAR1 (0.44) | FFAR1FFAR4CYP1A2KDM4ENPC1 | |
| SCHEMBL9862689 | 0.88 | CYP4F2 (0.45) | FFAR1CYP1A2KDM4ENPC1LMNA | |
| SCHEMBL7183632 | 0.83 | FFAR1 (0.52) | FFAR1FFAR4CYP1A2KDM4ENPC1 | |
| SCHEMBL7187213 | 0.82 | FFAR4 (0.47) | FFAR1FFAR4CYP1A2KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021414-A | Antiestrogen | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-06-04 | — | — | US | disclosed |
| US-4732912-A | ANTIESTROGENS, ANTITUMOR AGENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-03-22 | — | — | US | disclosed |
| EP-0124369-B1 | PHENOL DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-06-24 | — | — | EP | disclosed |
| EP-0124369-A1 | Phenol derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-11-07 | — | — | EP | disclosed |