Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9862381 | 1.00 | ALDH1A1 (0.45) | ALDH1A1HPGDCYP1A2CYP2C19HSD17B10 | |
| SCHEMBL9862564 | 0.91 | FFAR1 (0.50) | ALDH1A1HPGDCYP1A2CYP2C19HSD17B10 | |
| SCHEMBL9862517 | 0.90 | FFAR1 (0.51) | ALDH1A1HPGDCYP1A2CYP2C19HSD17B10 | |
| SCHEMBL10451931 | 0.88 | FFAR1 (0.48) | CYP1A2SMN1; SMN2LTB4RFFAR1PPARD | |
| SCHEMBL9862466 | 0.87 | PTGS1 (0.53) | ALDH1A1CYP1A2SMN1; SMN2FFAR1PPARG | |
| SCHEMBL9862483 | 0.87 | PTGS1 (0.53) | ALDH1A1CYP1A2SMN1; SMN2FFAR1PPARG | |
| SCHEMBL10452177 | 0.85 | FFAR1 (0.44) | CYP1A2SMN1; SMN2LTB4RFFAR1PTGS1 | |
| SCHEMBL9862551 | 0.82 | LMNA (0.47) | ALDH1A1HPGDHSD17B10SMN1; SMN2SLC2A1 | |
| SCHEMBL9862689 | 0.82 | CYP4F2 (0.45) | ALDH1A1HPGDCYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL5398432 | 0.80 | SLC2A1 (0.38) | ALDH1A1HPGDCYP1A2CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021414-A | Antiestrogen | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-06-04 | — | — | US | disclosed |
| US-4904661-A | ANTIESTROGENS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-27 | — | — | US | disclosed |
| US-4732912-A | ANTIESTROGENS, ANTITUMOR AGENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-03-22 | — | — | US | disclosed |
| EP-0124369-B1 | PHENOL DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-06-24 | — | — | EP | disclosed |
| EP-0124369-A1 | Phenol derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-11-07 | — | — | EP | disclosed |