SCHEMBL9862736

SCHEMBL9862736

CC1CC(=O)OC(C(O)CO)C1

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.38
PRKCA P17252 4/20 0.35
LMNA P02545 2/20 0.35
MAPT P10636 1/20 0.35
MANBA O00462 1/20 0.35
THRB P10828 1/20 0.35
HIF1A Q16665 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18855273 0.82 SMN1; SMN2 (0.43) SMN1; SMN2THRB
SCHEMBL4749440 0.77 LMNA (0.42) LMNAMAPTMANBATHRBHIF1A
SCHEMBL8149511 0.77 LMNA (0.42) LMNAMAPTMANBATHRBHIF1A
SCHEMBL12202936 0.76 SMN1; SMN2 (0.44) SMN1; SMN2THRB
SCHEMBL12650414 0.76 SMN1; SMN2 (0.44) SMN1; SMN2THRB
SCHEMBL12897962 0.71 SMN1; SMN2 (0.43) SMN1; SMN2PRKCA
SCHEMBL8378158 0.71 PRKCA (0.48) PRKCALMNAMAPTMANBATHRB
SCHEMBL8776236 0.71 PRKCA (0.48) PRKCALMNAMAPTMANBATHRB
SCHEMBL14520404 0.71 SMN1; SMN2 (0.43) SMN1; SMN2PRKCA
SCHEMBL8142299 0.71 PRKCA (0.48) PRKCALMNAMAPTMANBATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4997656-A Layer containing heat-and water-sensitive amphiphilic polymer and biologically active agent TAKIRON CO., LTD. (JP) 1991-03-05 US disclosed