Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.61 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.61 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.61 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.61 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.61 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | ESRRG | P62508 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | GFER | P55789 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9717433 | 0.92 | POLB (0.68) | POLBALDH1A1NPC1RAB9AMAPK1 | |
| SCHEMBL8142775 | 0.88 | POLB (0.58) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7087881 | 0.88 | HDAC1 (0.75) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11756884 | 0.88 | HDAC1 (0.75) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL1161862 | 0.86 | GFER (0.64) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL29833827 | 0.84 | POLB (0.74) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL3000922 | 0.83 | POLB (0.58) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL19133487 | 0.83 | HDAC3 (0.59) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL164070 | 0.83 | L3MBTL1 (0.65) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL6207746 | 0.83 | L3MBTL1 (0.70) | POLBALDH1A1NPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5002960-A | Viricides for combating picornaviruses | STERLING DRUG, INC. (US) | 1991-03-26 | — | — | US | disclosed |
| US-4939267-A | Viricides | STERLING DRUG INC. (US) | 1990-07-03 | — | — | US | disclosed |
| US-4843087-A | OXAZOLINYL COMPOUNDS; RHINOVIRUSES AND PICORNAVIRUSES | STERLING DRUG INC. (US) | 1989-06-27 | — | — | US | disclosed |
| EP-0083256-B1 | BENZAMIDE DERIVATIVES | KOWA COMPANY, LTD. (JP) | 1986-02-26 | — | — | EP | disclosed |
| US-4448989-A | N-Nitroxyalkylene benzamide derivatives | KOWA COMPANY, LTD. (JP) | 1984-05-15 | — | — | US | disclosed |
| EP-0083256-A1 | Benzamide derivatives | KOWA COMPANY, LTD. (JP) | 1983-07-06 | — | — | EP | disclosed |