Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | NAAA | Q02083 | 2/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.59 |
| ▸ | ESRRG | P62508 | 2/20 | 0.59 |
| ▸ | MLYCD | O95822 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19525772 | 0.95 | DRD2 (0.60) | L3MBTL1SMN1; SMN2NAAAHDAC3HDAC1 | |
| SCHEMBL16350299 | 0.95 | L3MBTL1 (0.73) | L3MBTL1SMN1; SMN2NAAAHDAC3HDAC1 | |
| SCHEMBL337999 | 0.93 | L3MBTL1 (0.76) | L3MBTL1SMN1; SMN2NAAAHDAC3HDAC1 | |
| SCHEMBL7271142 | 0.93 | L3MBTL1 (0.76) | L3MBTL1SMN1; SMN2NAAAHDAC3HDAC1 | |
| SCHEMBL7263385 | 0.93 | L3MBTL1 (0.76) | L3MBTL1SMN1; SMN2NAAAHDAC3HDAC1 | |
| SCHEMBL338163 | 0.93 | L3MBTL1 (0.76) | L3MBTL1SMN1; SMN2NAAAHDAC3HDAC1 | |
| SCHEMBL11035322 | 0.93 | L3MBTL1 (0.76) | L3MBTL1SMN1; SMN2NAAAHDAC3HDAC1 | |
| SCHEMBL338174 | 0.93 | L3MBTL1 (0.76) | L3MBTL1SMN1; SMN2NAAAHDAC3HDAC1 | |
| SCHEMBL337535 | 0.93 | L3MBTL1 (0.76) | L3MBTL1SMN1; SMN2NAAAHDAC3HDAC1 | |
| SCHEMBL7270311 | 0.93 | L3MBTL1 (0.76) | L3MBTL1SMN1; SMN2NAAAHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639111-A1 | ADSORPTION MATRICES | KEM-EN-TEC A/S (DK) | 1995-02-22 | — | — | EP | claimed |
| EP-0404039-B1 | PHARMACEUTICALS CONTAINING DI-TERT.BUTYLHYDROXYPHENYL-DERIVATIVES AND NEW DERIVATIVES | Roche Diagnostics GmbH (DE) | 1993-01-13 | — | — | EP | claimed |
| WO-1992016292-A1 | ADSORPTION MATRICES | KEM-EN-TEC A/S (DK) | 1992-10-01 | — | — | WO | claimed |
| US-9856210-B2 | Pharmaceutical composition for prevention and treatment of amyotrophic lateral sclerosis | KYOTO UNIVERSITY (JP) | 2018-01-02 | — | — | US | disclosed |
| EP-2611437-B1 | PHARMACEUTICAL COMPOSITION FOR PREVENTION AND TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS | UNIV KYOTO (JP) | 2017-03-29 | — | — | EP | disclosed |
| US-20130225642-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTION AND TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS | KYOTO UNIVERSITY (JP) | 2013-08-29 | — | — | US | disclosed |
| EP-2611437-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTION AND TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS | Kyoto University (JP) | 2013-07-10 | — | — | EP | disclosed |
| WO-2012029994-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTION AND TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS | KYOTO UNIVERSITY (JP) | 2012-03-08 | — | — | WO | disclosed |
| US-20110076613-A1 | RESIN COMPOSITION FOR LASER ENGRAVING, RELIEF PRINTING PLATE PRECURSOR FOR LASER ENGRAVING AND METHOD FOR PRODUCING THE SAME, AND RELIEF PRINTING PLATE AND METHOD FOR MAKING THE SAME | FUJIFILM CORPORATION (JP) | 2011-03-31 | — | — | US | disclosed |
| US-20110076613-A1 | RESIN COMPOSITION FOR LASER ENGRAVING, RELIEF PRINTING PLATE PRECURSOR FOR LASER ENGRAVING AND METHOD FOR PRODUCING THE SAME, AND RELIEF PRINTING PLATE AND METHOD FOR MAKING THE SAME | FUJIFILM CORPORATION (JP) | 2011-03-31 | — | — | US | disclosed |
| EP-0544908-B1 | THERMOPLASTIC ELASTOMER COMPOSITION | SUMITOMO CHEMICAL CO (JP) | 1996-01-31 | — | — | EP | disclosed |
| EP-0594845-A1 | AROMATIC OLIGOMER AND PRODUCTION THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-05-04 | — | — | EP | disclosed |
| US-5292810-A | graft polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-03-08 | — | — | US | disclosed |
| EP-0544908-A1 | THERMOPLASTIC ELASTOMER COMPOSITION | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1993-06-09 | — | — | EP | disclosed |
| EP-0511385-A1 | THERMOPLASTIC GRAFT COPOLYMER AND PRODUCTION THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-11-04 | — | — | EP | disclosed |
| WO-1992016292-A1 | ADSORPTION MATRICES | KEM-EN-TEC A/S (DK) | 1992-10-01 | — | — | WO | disclosed |
| EP-0345728-A2 | Dye composition for keratinous fiber | Kao Corporation (JP) | 1989-12-13 | — | — | EP | disclosed |
| US-4230606-A | Polyoxymethylene molding composition containing melamine formaldehyde polycondensate | DEUTSCHE GOLD -UND SILBER-SCHEIDEARSTALT VORMALS ROESSLER (DE) | 1980-10-28 | — | — | US | disclosed |
| US-4139575-A | AND ANTIOXIDATION AGENT; IMPROVED THERMAL STABILITY | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1979-02-13 | — | — | US | disclosed |
| US-4098709-A | LUBRICANTS | ROHM AND HAAS COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130225642-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTION AND TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS | SMN1; SMN2, SOD1, SOD3 | L3MBTL1 1654/4885SMN1; SMN2 1/4885NAAA 2182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.